Optimizing Immunopeptide Analysis Sample Preparation in Needle Biopsy Size Tissue Samples with AFA® Technology

In this webinar, Dr. Penney Gilbert from the University of Toronto explains how her group has uncovered regulators of muscle hypertrophy by inducing exercise-like rounds of contractions in their 3D skeletal muscle models.

Food fraud is estimated to cost the world economy more than $49 billion per year. The 2013 horse meat scandal alone was reported to cost the UK economy more than £1 billion. The effects of food adulteration reach much further than just these serious economic consequences. The Chinese infant formula scandal, which led to multiple mortalities and hundreds of thousands of babies hospitalized, brought into focus the health implications of economically motivated adulteration. Therefore, stakeholders in the food industry should be stepping up to help eliminate this global problem, not only to protect company brand identity but also to safeguard the well-being of consumers. A key aim of the scientific community should be to arm these stakeholders with the appropriate tools to make economically motivated food adulteration a thing of the past. New approaches are needed to help tackle food adulteration. Traditional targeted methods are failing to keep up with the actions of fraudsters, who are numerous and are active at multiple points throughout the globalized supply chain. There is now a general movement toward non-targeted methodologies to detect food adulteration. Instead of looking for individual components or analytes, non-targeted methods work by taking a much more holistic approach. In many ways the aim is to model normality for a commodity, then look for differences present in a suspect sample that is outside of this normal. In this way, if a fraudster changes what they are using to adulterate with, the analyst will still be able to detect an anomaly.

After watching the webinar, participants will be familiar with the consensus definition of arrhythmic mitral valve prolapse complex and will be able to discuss its evaluation, risk stratification, and management.

Attribute Sciences, Process Development, Amgen Biopharmaceuticals are drugs manufactured by growing genetically engineered cells in bioreactors to produce a therapeutic protein. Plastic single-use bioreactors are of interest to biopharmaceutical drug manufacturers due to their significant environmental and cost benefits and flexibility over stainless steel bioreactors. Effect of plastics on the biomanufacturing process is not yet completely understood. A case study on extractables from single-use bioreactors/bags and the impact on cell culture performance will be presented.