In Situ Bioremediation and In Situ Chemical Reduction for Remediation of 1,2,3-Trichloropropane in Groundwater

Complex macromolecules are becoming a mainstay of pharmaceutical strategy, and the ability to successfully develop these biologics into viable commercial drugs is accelerating at a significant rate.

Gain an understanding of how to help maintain the proper ethical pain management of patients. We are practicing in the midst of a national crisis in which every day over 130 people in the US die of overdosing from narcotic prescriptions overdose, heroin, and other related drugs. The pain was described as the "5th vital sign" by some drug companies in the 1990s and stated that patients would not be addicted to pain killers and providers began to overprescribe them in order to adequately treat pain. Approximately one-third of the chronic opioid user for none malignant pains misuse them. The incidence of neonatal abstinence syndrome has been on the rise due to widespread opioid use. CDC has published new guidelines as for how to counteract this crisis and regulatory agencies including states medical boards and DEA has increased enforcement against irresponsible and fraudulent opioid prescription writers to include license revocations and jail terms.

There is a clear call to automate manufacturing for cell and gene therapy products, but when should you automate? In this session, we will consider the shifting priorities as you move from product development towards clinical manufacturing and discuss how choosing the right type of automation can create immediate impact without compromising flexibility. Case studies in adherent and suspension cell expansion, gene modification and cell secretome production will be presented.

This technical video provides an overview of the methodologies, tools, and reagents used to generate multicellular tumor spheroids. Specifically, this video discusses the benefits of Cultrex® extracellular matrices for spheroid formation and analysis. Technical tips are provided for using colorimetric and fluorometric assays to evaluate cell proliferation and invasion of spheroids. This protocol video was originally recorded by Dr. Gabriel Benton at Trevigen, Inc. The Trevigen portfolio, including tools for creating 3-D and spheroid cultures, is now a part of R&D Systems, a Bio-Techne brand.