Custom LNP formulation development - The new Early Formulation Screening Service as a key partner for success

Custom LNP formulation
Nucleic acids are known to be fragile payloads. To enable their safe and efficient delivery into cells, the RNA payload needs to be “packed” into a delivery vehicle, the lipid nanoparticles (LNP). This webinar gives insight into our capabilities for customized LNP formulation development for novel therapeutic modalities.
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OTHER ON-DEMAND WEBINARS

Using Peptones to Achieve Diverse and Demanding Bioproduction Goals

Becton Dickinson

As bioproduction requirements advance, it is critical to have consistent, high-quality media and supplements that continue to meet evolving industry needs. Peptones have been successfully used in bioproduction applications for more than 30 years to meet diverse and demanding production requirements. Their unique nutritional profiles and usage flexibility make peptones ideal components for creating a robust bioprocess. Join us for this exciting new GEN webinar that will demonstrate the benefits of peptones and how they can be used to enhance process performance and consistently yield a high-quality product.
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Soft Tissue Cancer-IHC Webinar

Merck KGaA

Soft tissue tumors are a broad group of neoplasms that involve the connective tissue of the body. Each year, over 13,000 people in the US are diagnosed with soft tissue sarcomas and over 5,000 people succumb to the malignancy. Because soft tissue sarcomas are very ambiguous and amorphous, many time sarcomas are classified as an uncertain type. Advances in immunohistochemistry, as well as the utility of novel markers such as TFE3, TLE1, MyoD1, and MUC4, have aided pathologists in classifying these soft tissue tumors. This discussion will cover the key facts and statistics about soft tissue tumors and what role IHC plays in these difficult diagnoses.
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Biomechanics and Epidemiology of Shoulder Injuries

In this presentation we will breakdown the fundamental motions and biomechanics of the shoulder. After discussing the biomechanics of the shoulder, we will explore epidemiology research regarding the risk of shoulder injuries.
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Strategies to normalize miRNA expression in serum and plasma

Thermo Fisher Scientific - Applied Biosystems

MicroRNA(miRNA) are short non-coding single-stranded RNA molecules that regulate gene expression at the post-transcriptional level. They are known to play a critical role in multiple biological processes including proliferation, differentiation, apoptosis, and hematopoiesis. Dysregulation of miRNA expression, therefore, is associated with a number of pathological conditions such as inflammation, cardiovascular diseases, neurological disorders and several types of cancers. miRNAs are also found to be extremely stable in body fluids such as serum, plasma, urine, breast milk, and saliva. Extracellular miRNAs are either packed into exosomes or loaded into high-density lipoproteins or bound by AGO2 proteins outside on vesicles. These modes of action protect miRNAs from degradation and improve their stability. Because of their stability in body fluids, miRNAs are gaining importance as biomarkers in liquid biopsies.
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