genengnews
Biophysical and chemical properties are critical factors that can dictate success or failure in the development of therapeutic antibodies. These attributes and all the functional characteristics of antibodies depend on amino acid sequence, post-translational modifications, and the solution environment. Early quality control and risk assessment of biophysical parameters help prevent failure in later stages of antibody development.
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Autoantibody assays may have significant differences due to the heterogeneity of autoantibodies, including epitope specificity, isotype, and affinity/avidity.
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DNA assembly is commonly performed in the build step of the design-build-test-learn cycle at the core of synthetic biology. In many assembly workflows, DNA is assembled into gene fragments, which are then assembled into larger constructs, often plasmids.
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siremlab
For common groundwater contaminants such as chlorinated ethenes, demonstrating biodegradation activity based on detection of daughter products is straightforward, since the products are readily discernible from background sources. However, this is not the case for all contaminants. With chlorinated methane’s (i.e., carbon tetrachloride, chloroform, and dichloromethane), for example, anaerobic reductive dichlorination is not the only degradation pathway.
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