Scientists demonstrate use of ultrasound to alter inflammatory and metabolic response

GE Research and Feinstein Institute for Medical Research bioelectronic medicine teams have demonstrated potentially breakthrough non-invasive methods to regulate dysfunction in the body's metabolic or inflammatory control systems using ultrasound. The findings were reported in this week's edition of Nature Communications. This article follows a medical first from The Feinstein Institute and GE Research to read what nerves are saying about inflammation in the body. Bioelectronic medicine combines neuroscience, molecular biology, and bioengineering to tap into the nervous system to treat disease and injury without the use of pharmaceuticals. Published bioelectronic medicine research has shown implanted devices stimulated nerves for therapeutic outcome. This most recent paper discusses the use of a non-invasive ultrasound technique to stimulate nerve features directly within target organs in a very precise manner. "We have found that using ultrasound in very specific and targeted ways, we can reduce inflammatory markers and alter metabolism," said Chris Puleo, a GE biomedical engineer and co-author of the Nature Communications article. "In our studies, we show that applying ultrasound to a specific target in the spleen altered inflammatory markers that can cause arthritis, IBD and other ailments.