INDUSTRIAL IMPACT

Portal Innovations Expands Chicago Operations Triples Space in Fulton Labs

Portal Innovations | February 03, 2022

Portal Innovations continues its momentum in Chicago by launching the second phase of its operations with the opening of 35,000 square feet of premier wet and dry lab and office space at 400 North Aberdeen in Fulton Labs. The new facility will allow Portal, a life sciences venture development engine, to grow and scale its investment in early-stage biotech companies in Chicago.

Portal has tapped Patrick Flavin to serve as President of its flagship Chicago operation. With over 20 years of experience building high-performing teams and collaborations with corporate partners in several public and private life sciences companies, Patrick brings his seasoned biotech-entrepreneurial experience to navigate Portal’s portfolio expansion. Patrick was the founding Executive Director at MATTER and currently serves as a Managing Director at Portal.

I am excited to partner with Patrick as we continue to build Portal into a premier platform of investment in transformative companies with the best innovators, entrepreneurs, academic institutions, and venture capitalists. Patrick’s experience and vision are crucial for Portal to reach the next level here in Chicago.”

 Portal Founder and CEO John Flavin


Through its “Crafted Capital” model, Portal invests seed financial funding, offers access to fully equipped wet and dry lab space, and provides management expertise to leading scientific and entrepreneurial founders. Portal is building a valuable portfolio of life sciences companies at the seed to series A investment stage for long-term value creation.

Portal has partnered with Trammell Crow Company, one of the largest commercial real estate developers in the United States, to catalyze the Chicago regional life sciences ecosystem at the Fulton Labs Campus and is currently investing in and supporting companies in its existing 11,000 square feet of wet and dry lab and office space at 1375 West Fulton Street.

“I am thrilled to expand our operations in Fulton Labs during a very exciting time for breakthroughs in biotech,” said Patrick Flavin. “Portal’s expansion of lab and office space will accelerate our ability to invest in, house, and support the promising life sciences companies that are emerging from the region’s top tier research institutions.”

About Portal Innovations
Portal Innovations is a premier venture development engine that bridges scientific ideation in life sciences, medtech, and bioinformatics through commercial proof of concept by delivering crafted capital, including seed funding, specialized equipment, lab space, and management expertise to high-potential early-stage companies. 

Spotlight

Capsular polysaccharides (CPS) of encapsulated bacterial pathogens can give rise to an effective immune response in humans and are commonly used in vaccine production. This whitepaper offers an overview of modern tools and technologies that can facilitate CPS based vaccine production. An alternative purification approach based on chromatography, replacing many of the ethanol and phenol extraction steps of the traditional process, is also presented. Using the proposed purification platform, 28 different CPS of three different species could be processed to high purity and yield in a secure and environmentally friendly way


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RESEARCH

Medolife Rx Announces Changes to Management and Improvements to AELIA’s Marketing Efforts

Medolife Rx, Inc. | February 07, 2022

Medolife Rx, Inc. a global integrated biopharmaceutical company with manufacturing, and consumer product distribution, which is a majority owned subsidiary of Quanta, Inc. that the Company is in progress of revamping their online marketing platform, starting off with a change in the marketing and brand development for their AELIA brand wellness products that utilize the company’s polarized ingredients. Medolife believes these changes will bring greater product awareness and improved online presence. The Company’s manager of marketing and brand development, Maggie Dumais, has stepped down from their position under mutual agreement with the Company. In order to support the Company’s vision of a new marketing strategy, Medolife is finalizing an agreement with a new director of marketing and brand development, whose name will be announced at a later date. “We are excited with the new direction that the Company is taking with its AELIA products and expect a positive outcomeThe Company’s values, goals and plans will be presented in a way that reflects our mission to promote health and well-being with our expanding line of products.” Medolife CEO Dr The Company also hired a new team to oversee the overhaul of AELIA’s websites, product listings and social media presence. The Company hopes that, with the help of these experienced professionals, their online platforms will see an increase in sale conversions and consumer feedback. Medolife thanks its shareholders and clients for believing in them. The Company will have more positive news coming out soon. About Medolife Rx Medolife Rx, Inc. is a global biotechnology company with operations in clinical research, manufacturing, and consumer products. Medolife Rx was created through the merger of Medolife, a private company founded by Dr. Arthur Mikaelian, who pioneered the unlaying polarization technology, and Quanta, Inc., a direct-to-consumer wellness product portfolio company. The Company’s lead clinical development programs include Escozine®, a proprietary formulation consisting of small molecule peptides derived from Rhopalurus princeps scorpions, which is amplified by the Company’s polarization technology and is being researched as a treatment of various indications, including COVID-19 and cancer. The Company intends to pursue product registration and drug approval in multiple countries. Through its subsidiary AELIA, Medolife manufactures and distributes consumer wellness products in consumer areas such as pain relief, beauty, and general wellness. AELIA products are designed using Dr. Mikaelian’s polarization technology, which applies advances in quantum biology to increase the potency of active ingredients. Ultimately, Quanta's mission is to deliver better, more effective ingredients to elevate product efficacy, reduce waste, and facilitate healthier, more sustainable consumption. Beyond its own clinical and consumer applications, the polarization technology used by Medolife and its subsidiaries has many potential applications. From potentiating bio-ingredients, to producing more-effective carbon-trapping plants, to transformative anti-aging solutions, Medolife could have the opportunity to upend how commercial and pharmaceutical products are made and increase their benefits, while decreasing their chemical concentration.

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INDUSTRIAL IMPACT

Lummus and Synthos Advance Bio-Butadiene Technology Development to Produce Sustainable Rubber

Lummus Technology, LLC | February 14, 2022

Lummus Technology announced that its Green Circle business and Synthos S.A. have reached a major milestone in the development of advanced bio-butadiene technology. After completing a successful feasibility study in 2021, Lummus and Synthos have concluded that the bio-butadiene technology is ready for implementation, and the companies have agreed to move into the engineering and design phase of the project. Given the confidence in the technology and the strong market demand for renewable materials, Synthos has committed to building a plant with a capacity of 40,000 metric tons of bio-butadiene per year – twice as much as the companies had originally planned. In addition to the plant capacity expansion, Synthos has confirmed that it will license BASF's butadiene extraction technology from Lummus and leverage Lummus' digitalization capabilities for operational efficiency and reliability. "Since Lummus began collaborating with Synthos last year, it has become evident that this technology has the potential to be the new standard in our industry due to its renewable sourcing, production efficiency and low carbon footprint. The petrochemical industry is quickly adjusting to ambitious sustainability requirements, and at Lummus we continue to lead this change on multiple fronts. The commercialization with Synthos of this bio-technology for more sustainable rubber products is one of several sustainable process solutions that are making a positive impact." Leon de Bruyn, President and Chief Executive Officer of Lummus Technology "Synthos is making great strides in developing a synthetic rubber product portfolio with a significantly reduced environmental footprint. Entering the next phase of our collaboration with Lummus is another step toward our commitment to help our customers achieve their performance and sustainability goals," said Matteo Marchisio, Synthetic Rubber Business Unit Director, Synthos. "We believe the availability of sustainable synthetic rubber made from bio-butadiene will play an important role in the industry's ability to meet the demands of modern mobility, and we are proud to partner with Lummus Technology to lead the way." Synthos is a global leader in the development and production of synthetic rubber for tires and technical rubber goods and is committed to providing its customers with high-performance material solutions with a lower environmental footprint. In 2021, Green Circle and Synthos announced that they will collaborate on the development and commercialization of bio-butadiene derived from bio-ethanol to enable the production of value-added, more sustainable synthetic rubber. A subsidiary of Lummus, Green Circle is a leader in commercializing and developing breakthrough solutions to address the key pillars of the energy transition, including end-of-life waste plastics recycling, production of bio derived sustainable chemicals, and decarbonization strategies for existing and new assets. About Lummus Technology Lummus Technology is the global leader in developing process technologies that make modern life possible and focus on a more sustainable, low carbon future. Lummus is a master licensor of clean energy, petrochemical, refining, gas processing and renewable technologies, and a supplier of catalysts, proprietary equipment, digitalization and related lifecycle services to customers worldwide. About Synthos Synthos S.A. is a chemical producer and a major player in the global synthetic rubber market. Synthos S.A. Capital Group's business includes the production and sales of chemical products used as raw materials and intermediates in a wide range of industries, particularly in the tire industry, the construction industry and the packaging industry.

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MEDICAL

Relevate Health Acquires ConneXion360

Relevate Health | April 26, 2022

Relevate Health solidifies its position as the market leader in Healthcare Professional (HCP) omnichannel engagement with the acquisition of Dallas-based ConneXion360. With this acquisition, Relevate Health now provides its omnichannel solutions and agency services to more than 185 brands from 90 pharmaceutical, biotech, and medical device manufacturers, as well as 24 hospital systems. The addition of ConneXion360 expands the Relevate Health suite of HCP engagement marketing solutions for its clients with precision messaging at the point-of-care and point-of-prescribing and Key Account Messaging for 1:1 engagement, complemented by ConneXion360's National Broadcast capabilities and OnDemand platform for "non-personal" engagement. The combination enables Relevate Health's clients to gain access to difficult-to-reach health systems and HCPs via ConneXion360's industry-leading Treatment Perspectives Recruitment Network. These proven solutions will be integrated into Relevate Health's proprietary ElevatedRelevance℠ data platform to cultivate unique and actionable content, market selection, and Key Opinion Leader identification insights for its clients. Relevate Health's comprehensive suite of data-driven HCP Engagement solutions solves the last-mile challenge that many brands face in connecting their creative campaign to target HCP audiences. Relevate Health's digital activation services and marketing solutions plug into existing omnichannel infrastructure and spans the gamut from 1:1 to mass engagement. Bringing ConneXion360's 1:1 engagement, Key Account Messaging, immersive video, and national broadcast capabilities into the Relevate Health suite of products and technology offer new brand-building opportunities for our clients, Quite simply, it means more access to HCPs by the Reps, MSLs, and KAMs, richer opportunities to scale nationally using local data, and deeper omnichannel engagement. For clients seeking a digital-first omnichannel agency, we complement our highly differentiated engagement solutions with class-leading agency services, and digital activation capabilities that help our clients achieve their ambitious growth objectives." Relevate Health CEO Jeff Spanbauer. Relevate Health delivers innovative, integrated HCP omnichannel engagement solutions that are configured to meet clients' specific market challenges. Its unmatched capabilities in "non-personal" promotion, immersive video, peer-to-peer engagement, field rep access, and field rep enablement make Relevate Health the premier marketing partner. Relevate Health delivers precision, segmented, and scalable engagement solutions that overcome the increasing HCP access hurdles. Relevate Health is known for its use of data and machine learning to create locally relevant messages that are scalable, By adding ConneXion360's Treatment Perspectives Recruitment Network and our portfolio of proprietary Treatment Perspectives National & Local HCP Message Engagement Solutions, we can engage target HCPs with more precision, personalization, and relevancy at both national & local levels. Our clients now have access to a single premier partner with a full suite of product-driven, data-based solutions that deliver proven brand growth and extraordinary ROI among previously hard-to-engage HCP audiences." George Griffith, Co-Founder & CEO of ConneXion360. The acquisition of ConneXion360 marks the third transaction by Relevate Health since taking on funding from Denver-based private equity firm Mountaingate Capital in late 2020. Relevate Health's comprehensive system of marketing solutions enables clients of all sizes to deploy a platform that fits their needs. With this acquisition, Relevate Health becomes a single omnichannel partner that addresses the full range of HCP engagement challenges, from 1:1 to National Broadcast, providing field personal as well as brand, digital, and medical leaders with solutions that change HCP's behavior and deliver benchmark beating ROI. Relevate Health, founded in 2007, is an award-winning healthcare marketing agency for pharmaceutical, biotech, and medical device brands, recognized by MM&M, PM360, MedAdNews, and more. ConneXion360 is the leading Health System and HCP Recruitment Network that specializes in creating access for its clients to Health Care Professionals through its proprietary Treatment Perspectives Recruitment Network, National Broadcast platforms, and precision messaging at the point-of-care and the point-of-prescribing.

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MEDICAL

Slingshot Biosciences, Inc. Partners With Cambridge Bioscience to Distribute Synthetic Cells Throughout United Kingdom and Ireland

Slingshot | June 16, 2022

SLINGSHOT BIOSCIENCES, INC. the makers of synthetic cells that bring consistent precision and accurate control to replace inconsistent blood and tissue controls for use in flow cytometry and other biotech markets, today announced they have extended their distribution channel through a new agreement with Cambridge Bioscience, a UK-based specialist distributor of life science research tools. The agreement entitles Cambridge Bioscience to the right to distribute and resell Slingshot Bio’s products in the United Kingdom and Ireland. Through Cambridge Bioscience’s network of customers, Slingshot Bio will be able to establish its presence in the United Kingdom and Ireland market with the well-established presence and expertise of Cambridge Bioscience which has been selling into flow cytometry for many years. Cambridge Bioscience’s network will provide us with the market penetration needed to reach our full sales potential. Slingshot Biosciences has considered many distribution partners and we are confident that Cambridge Bioscience’s extensive knowledge in the field, prominent presence, and large customer base will help us leverage our position in the flow cytometry market.” Jeffrey Kim, CEO & Founder. About Slingshot Biosciences, Inc. Founded in 2012, Slingshot Biosciences is a fast-growing life sciences company with a platform technology and paradigm-shifting mission to make synthetic cells the gold standard for all cell-based applications—including diagnostics, and adoptive cell therapy development and instrument calibration.

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Spotlight

Capsular polysaccharides (CPS) of encapsulated bacterial pathogens can give rise to an effective immune response in humans and are commonly used in vaccine production. This whitepaper offers an overview of modern tools and technologies that can facilitate CPS based vaccine production. An alternative purification approach based on chromatography, replacing many of the ethanol and phenol extraction steps of the traditional process, is also presented. Using the proposed purification platform, 28 different CPS of three different species could be processed to high purity and yield in a secure and environmentally friendly way

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