Phanes Therapeutics reveals a new bispecific antibody technology platform at BIO Digital 2020

Phanes Therapeutics, Inc. (Phanes), an emerging leader in innovative discovery research in immuno-oncology announced today that it has developed a proprietary bispecific antibody technology platform, PACbodyTM, which enables construction of a bispecific antibody using any pair of monoclonal antibodies (mAbs) while maintaining the IgG-like structure. The technology was presented at the BIO Digital 2020. "The beauty of the PACbodyTM bispecific antibody platform is that it's a 'plug and play' technology to quickly make an IgG-like bispecific antibody – the native structure of both arms of the bispecific antibody is maintained," said Dr. Hui Zou, PhD, Chief Scientific Officer (CSO) of Phanes Therapeutics. Phanes built two out-licensing partnerships last year, including a licensing agreement with Hanmi Pharmaceutical Co., LTD (Hanmi) that allows Hanmi to evaluate and license antibody sequences against an undisclosed target from Phanes and use them in multiple projects, and a licensing agreement that allows Fosun Kite (a joint venture by Kite/Gilead and Fosun Pharma) to use a collection of high-affinity humanized antibodies and single-chain fragment variable (scFv) molecules targeting two novel cancer antigens for the development and commercialization of innovative CAR-T products for solid tumor treatments.