What’s Next in Preclinical Cancer Immunotherapy Research?

Many phenotypes and pathologies arise due to dysregulation of gene expression. Tracking mRNA levels and the means by which they are regulated helps to understand underlying mechanisms. For example, alterations in miRNA expression are associated with many human cancers. This has led many to believe that miRNA profiling can potentially be used to classify tumor subtypes making its potential as diagnostic, therapeutic, and prognostic biomarkers more promising.

Fluidigm introduced its Maxpar Human Immune Monitoring Panel Kit for comprehensive immune cell profiling in cancer and immune-mediated diseases. The immune monitoring kit contains 29 metal-labeled antibodies and reagents designed for deep immune profiling of human peripheral blood mononuclear cells in one tube. The single-tube assay enables combinatorial information to be obtained from each sample, eliminates daughter tube variation, and offers a simplified workflow that reduces hands-on time, the company says. The kit is designed for use with the Helios system for mass cytometry.

Dr. Kristin Comella, Chief Science Officer of U.S. Stem Cell, Inc. a leader in the development of proprietary, physician-based stem cell therapies and novel regenerative medicine solutions, today announced the successful launch of an open, livestream webinar series designed to inform and educate the public on the benefits and applications of stem cell therapy.

Interleukin-11 (IL-11) is an interesting and unique pleiotropic cytokine, originally characterized as a hematopoietic cytokine with thrombopoietic activity.