Antibodies have established themselves as one of the most important classes within the biologics space, and developing these therapeutics requires a series of successful decisions throughout the early-discovery process.
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ROCHE
Maize is one of the most economically important crops globally and much effort has been spent generating the high quality B73 reference genome. However, the 10 chromosome, 2.3 gigabase (Gb) B73 reference genome was a substantial challenge due to the fact it is comprised of 85% transposable elements, 75% of which are long terminal repeat (LTR) retrotransposons that share high sequence similarity and form nested repeat structures. Ultralong Oxford Nanopore Technology (ONT) holds the promise of traversing the complex repeat structures of maize and enabling rapid sequencing of new breeding lines.
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In the first installment of the ASBMB Publications Technique Talks webinar series, our speakers delve into different mass spectrometry approaches with a focus on proteomics and disease.
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The subcellular distribution and function of lipids remains a serious challenge to understanding biology. Two student presentations at a recent scientific conference highlighted a new innovation in mass spectrometry that improves organelle identification and a new function for ceramide-dependent mitophagy associated with aging in T cells.
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