The new wave in bio-based materials: maximum value from lignin with industry-specific fractions

PSCs represent an important tool in a wide range of applications, including basic research, disease modeling, drug discovery, and regenerative medicine. As stem cell cultures are very sensitive and respond to the smallest influence, stable culture conditions are crucial to maintain reliability and reproducibility of experimental data. In this educational webinar we will look at the different cultivation parameters, which can affect the viability and proliferation of PSCs during expansion. Join us to learn more about how to assess the quality of your stem cells and to preserve their pluripotency.

Cardiac excitation-contraction coupling is the process by which electrical excitation drives cardiomyocyte mechanical shortening. Following membrane depolarization, calcium influx through voltage-gated calcium channels triggers calcium release from intracellular stores. Increased cytosolic calcium binds to troponin, allowing sliding of actin thin filaments against myosin thick filaments. This results in myocyte contraction. Cytosolic calcium extrusion and sequestration induces myofilament relaxation, readying the cardiomyocyte to begin again. Understanding this tightly regulated process, as well as how perturbations disrupt it, is critical to understanding heart function and dysfunction.

Group A Streptococcus (Group A Strep) remains fairly unchanged and is well-understood by the scientific community. However, our methods of detection have significantly improved as have various options for testing. With so many advancements in the landscape of molecular diagnostics, it is vital for all healthcare institutions to thoroughly understand and appropriately plan for common and potentially, high volume tests. In this free webinar, the featured speaker will review and explore the topic of “The Group A Strep Diagnostic Algorithm” and support a closing Q&A session. As part of his discussion, he will define and review items such as testing requirements, the disease state, prevalence in specific demographics and geographies, disease implications, the benefits and drawbacks of various testing methodologies and the testing needs of today’s variety of healthcare settings.

Characterizing MSI status in challenging samples, including those with ambiguous results or small shifts, can be difficult. Endometrial and other cancers tend to have fewer, smaller marker shifts making MSI analysis cumbersome.