Single-Cell, Spatial, & In Situ Hi-Res Mapping of the Breast Cancer Tumor Microenvironment

Fossil fuels such as coal, petroleum, and natural gas are currently the gold standard of meeting our energy needs. High levels of fossil fuel consumption have led to depleted resources, increased cost, and high levels pollution. A Fossil-fuel based energy economy has been deemed unsustainable and, therefore, the adoption of sustainable and environmentally compatible energy sources is imperative. Molecular cloning has been used to engineer strains of microbes that can perform a range of processes needed to create sustainable biofuels such as ethanol as well as useful bioproducts. Due to the high throughput nature of microbial strain engineering, molecular cloning workflows are prone to human error, labor-intensive, and time consuming. These challenges create large bottlenecks resulting in low productivity. Strain engineering can benefit greatly from the increased productivity of an automated colony picker such as Molecular Devices QPix® 400 Series Microbial Colony Picker, which automatically picks up to 3000 colonies per hour or 30,000 colonies per day with automatic pick run data tracking and database management. For higher throughput and more walkaway time, there are custom design options for an automated work-cell that integrates user desired instrumentation, and robotic control with the QPix colony picker to improve productivity and eliminate bottlenecks.

Poor drug solubility is one of the most challenging issues in drug development. Up to 90 % of all newly discovered drugs show insufficient aqueous solubility in their crystalline form,

The COVID-19 pandemic has shown the world that the effectiveness of mRNA vaccine technology is undeniable. The potential for these vaccines to efficiently treat a wide range of communicable diseases is enormous, and the technology is poised to explode into the marketplace. However, effective mRNA vaccines are only as good as the materials and methodologies used to create them, as well as the analytical steps used to test their potency, stability, and clinical efficacy. Traditional analytical methods are slow and end up wasting investigators’ time and money. Advanced imaging and analysis platforms may hold the key to simplifying vaccine development and manufacturing bottlenecks, as they are fast and can be multiplexed to answer multiple scientific questions per analysis.

Learn new methods to optimize the process between anaerobic digestion and the combined heat and power engine. Vaisala’s Product Manager Antti Heikkilä explains in detail the crucial measurement points related to humidity, methane, and carbon dioxide, and demonstrates how biogas production can be more profitable while keeping operating expenses to a minimum.