Resetting Expectations for CAR-T Potency Assessment – A Novel Target Cell Killing-Based Approach

Resetting Expectations
Potency assays are an essential aspect of analyses of biotherapeutics, including CAR-T therapeutics. The potency assay format that will be used as a release assay for CTM (in a QC environment) needs to be as accurate, precise and robust as possible.
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OTHER ON-DEMAND WEBINARS

Food Safety Management Systems to Enhance Customer Experience

Food Safety Magazine

Restaurant cleanliness matters! It’s the most important driver of customer visitation (i.e., they come back more often and increase sales) and brand loyalty, just behind the importance of employee service and food quality attributes. Employee service, “cleanliness“, and how the employee cleans are important attributes that inform a customer’s perception of good service and hospitality. Food safety management systems that control food safety hazards can also directly influence restaurant facility cleanliness, employee service, and food quality, and can be leveraged to enhance the customer experience. This session will present a successful model to enhance both food safety management and customer experience in a restaurant environment.
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High-Throughput Multiplexed Screening of TCR Signaling Inhibitors

Intellicyt Corporation

T cells play a critical role in the adaptive immune response. In naive T cells, binding of the T-cell receptor (TCR) to peptides complexed with major histocompatibility complex triggers an intricate signaling mechanism leading to T-cell activation, proliferation, and production of cytokines. Modulating the TCR signaling pathway using biologics, small molecules, or genetic engineering is highly relevant to many therapeutic areas, including cancer immunotherapy, adoptive cell therapy, vaccine development, and autoimmune disease.
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Decoding the Vaginal Microbiome

This webinar explores the complexities of the vaginal microbiome and new opportunities for Next-Gen Sequencing in women's health diagnostics.
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Accurate Prediction of On- and Off-Target Cardiotoxicity with Human iPSC-Derived Cardiomyocytes

genengnews

Latent cardiovascular toxicity issues continue to plague late-stage drug discovery efforts, as well as commercially launched pharmaceutical success. Many current in vitro models lack, or incompletely recapitulate, important aspects of human cardiac biology, thus allowing certain toxicities to escape detection until the non-human primate and clinical trial stages of drug development. Induced pluripotent stem cell (iPSC) technology brings relevant human biology to the laboratory and with it, great promise for early predictive detection of cardiotoxicity.
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