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Probing Epigenomic Heterogeneity in Single Cells

The advent of single cell approaches for studying chromatin accessibility, including single-cell ATAC-seq and single-cell RNA-seq, has enabled characterization of epigenomes at single cell resolution. These studies contribute to a systems-level understanding of epigenomic variation at the single-cell level, allowing detection and assessment of an important driver of cell-to-cell heterogeneity.
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