Optimize Biotherapeutics Design with In Silico Techniques

Circular, Rep-encoding single-stranded (CRESS) DNA viruses were once thought to be a rare kind of viral genomic architecture. While some significant agricultural diseases were caused by circoviruses and geminiviruses, they are not typically human pathogens, and it was only when metagenomic methods that were not biased towards double-stranded DNA were widely used did we identify single-stranded DNA viruses ubiquitously.

In this webinar, Marie Piketty recalls that in recent years, several cases of interference caused by Biotin have been reported, concerning doses of thyroid hormones, but also other hormones, and other dosages. Biotin also called Vitamin B7, is a cofactor of several reactions to the carboxylase. Biotin present in multivitamin cocktails, does not present a risk of interference, but the use of Biotin at supraphysiological doses as a product of "beauty" (for hair, nails and skin), or at high doses as treatment in patients with multiple sclerosis can cause interference.

The subcellular distribution and function of lipids remains a serious challenge to understanding biology. Two student presentations at a recent scientific conference highlighted a new innovation in mass spectrometry that improves organelle identification and a new function for ceramide-dependent mitophagy associated with aging in T cells.

This webinar will provide an introduction to biotechnology products for regulatory affairs professionals.