Maize genome complexity traversed with Oxford Nanopore technology

Maize is one of the most economically important crops globally and much effort has been spent generating the high quality B73 reference genome. However, the 10 chromosome, 2.3 gigabase (Gb) B73 reference genome was a substantial challenge due to the fact it is comprised of 85% transposable elements, 75% of which are long terminal repeat (LTR) retrotransposons that share high sequence similarity and form nested repeat structures. Ultralong Oxford Nanopore Technology (ONT) holds the promise of traversing the complex repeat structures of maize and enabling rapid sequencing of new breeding lines.
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OTHER ON-DEMAND WEBINARS

Advancing Single-Use Technology Through Digitalization and Collaboration

As single-use technologies have been widely adopted by the pharmaceutical industry, there has been a corresponding shift in responsibility from end-users to suppliers.
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Best Practices For Viral Clearance Studies

When a developed virus filtration process is validated by viral clearance testing, the addition of a virus spike for just this purpose can lead to disappointing results.
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Innovation in the cloud: see what artificial intelligence can do for ICMs

esc365

After watching this webinar, participants will understand: how an artificial intelligence algorithm for implantable cardiac monitors is developed and validated; and the reliability of this approach and how it may result in a more efficient hospital workflow.
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Factors to Consider During Adaptation of a Manual Cell Line Development Workflow to Automation

Labroots

Mammalian cell line generation is a rate-limiting step in early CMC development and there is a constant desire to increase throughput. The implementation of automation is one way to increase throughput. This webinar will address some factors to consider during the process of automating a manual workflow including details of culture vessel changes, liquid handling adaptation, and changes of the cell line developer’s job during the process. With an end result of increased throughput, automation potentially allows cell line development to begin prior to final molecule selection. This can remove cell line development off the critical path of CMC development.
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