How Computational Life Sciences Enables Metagenomics Studies

While the importance of ligand-receptor binding kinetics on drug action is becoming well established, focus to date has been almost entirely on the role of the dissociation constant on drug efficacy and duration of action. The association rate constant, in contrast, has been largely overlooked, with many investigators still considering it diffusion-limited and equivalent across a compound series. This GEN webinar aims to remedy that by turning the spotlight onto the undervalued and oft-ignored association rate constant.

Because of its reliability, sensitivity and low cost, PCR has become the backbone of modern diagnostics. In recent years, researchers have ingeniously capitalized on the fundamental nature of PCR through multiplexing reactions saving reagent costs, precious samples, and user time. Multiplexing has also enabled pathogen screening and genotyping for much larger numbers of targets, thereby improving the breadth and utility of diagnostics. However, while multiplexing reactions can be a boon to lab productivity, they are not without their pitfalls.

We will introduce Chromassette® and an application example of an integrated rapid single pass process from harvest to purified bulk, a concept demonstrated by AbbVie. Chromassette is a stackable, single-use and pre-packed chromatography cassette with a supported bed, addressing the current key challenges in manufacturing. Chromassette enhances the separation capabilities of chromatography resins and combines it with the convenience of a modular cassette.

You will be hearing from a variety of Scientists from Wyatt Technology who will help explain some of the key advancements and improvements made in light scattering that we believe will provide future customers with state-of-the-art capabilities and unique benefits.