Summing up the ground-breaking work that researchers in the cell and gene therapy space are producing is easy if one follows the notion that “the most reliable way to predict the future is to create it.” In recent years, investigators have worked tirelessly to solve many of the fundamental challenges associated with these therapeutic modalities. Yet, innovation and success are an evolving process that address challenges during the drug discovery and development stages.
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GE Healthcare Life Sciences
Through genomic sequencing and analysis, clinicians can identify specific mutations present in a patient’s cancer cells and deliver personalized treatment based on the genetic information. Increased availability and lower costs of next-generation sequencing (NGS) and analysis, along with the on-going identification of an expanding array of cancer-related genetic mutations and biomarkers, are enabling exponential growth in the use of this diagnostic and therapy-targeting tool.
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Poor drug solubility is one of the most challenging issues in drug development. Up to 90 % of all newly discovered drugs show insufficient aqueous solubility in their crystalline form,
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Essen BioScience
Despite exciting recent developments in neuroscience, identifying novel, truly effective treatments for patients with neurological and psychiatric conditions remains highly challenging. There is a high unmet need for more translational models and advanced analytical techniques that afford greater biological insight and productivity.
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