Since the year of 2000, there’re 13 ADCs on the market and 9 of them were approved in the last three years. The enthusiasm of pharmaceutical and biotechnology companies for the research and development of ADC has been increasing.
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Monoclonal antibody-based therapeutics are well established in the pipelines of biopharmaceutical organizations and have decades of development ahead. However, not all of them have disclosed or confirmed amino acid sequences. Ultra-high-performance liquid chromatography mass spectrometry provides a powerful tool to obtain the sequence information to the residue level. Historically, the process has needed expert users and therefore was extremely low throughput and is often outsourced.
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statnews
The gene-edited babies controversy got all the headlines, but there’s a lot more going on with the technology known as CRISPR these days.
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insidescientific.com
In this webinar, Dr. Jiahui Yang provides an overview of antibody discovery platforms and discusses how single B cell sorting can be used to generate functional monoclonal antibodies for a range of applications including disease diagnosis and therapeutics.
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