Current Gold Standards for MSI Testing and the Clinical Relevance of the MSI-H Biomarker

Current Gold Standards
Historically MSI has been used to screen for Lynch syndrome, a dominant hereditary cancer propensity. Since 2015, MSI status has been rediscovered as a biomarker for immunotherapeutic response
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OTHER ON-DEMAND WEBINARS

Decoding the Vaginal Microbiome

This webinar explores the complexities of the vaginal microbiome and new opportunities for Next-Gen Sequencing in women's health diagnostics.
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The new wave in bio-based materials: maximum value from lignin with industry-specific fractions

biomarketinsights

The era of affordable sugars, renewable biochemical and bio-based materials from lignocellulosic feedstock are here. Enabling a paradigm shift from petroleum and change over to renewable biomass, the new fractionation technologies of lignin allow the entire biomass to be utilized. Lignocellulosic biomass – a variety of non-edible, woody materials – is the largest renewable reservoir of fermentable carbohydrates, aromatic compounds, and other chemical building blocks. With the new wave of biotechnology, controlled size, solubility, and activity of lignin can be achieved.
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Cancer Gene Expression Targets Validated Using Novel Histopathology Tools

genengnews

When assessing a potential biological therapeutic candidate, several histopathological technologies are typically employed. This ensures the target expression is validated in both normal and diseased tissues before proceeding with pre-clinical studies. Protein B is a transmembrane glycoprotein that is overexpressed in numerous cancers, including triple-negative breast cancer and is often correlated with the metastatic phenotype. In this GEN webinar, we will discuss the process involved in a typical molecular pathology laboratory. Control cell lines and the RNAScope® Assay were utilized to validate the immunohistochemistry protocol.
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A Neuroscientist’s Guide to Live-Cell Analysis: Techniques & Benefits

Essen BioScience

Despite exciting recent developments in neuroscience, identifying novel, truly effective treatments for patients with neurological and psychiatric conditions remains highly challenging. There is a high unmet need for more translational models and advanced analytical techniques that afford greater biological insight and productivity.
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