Clinically-Relevant Transporters, Clinical Probes and DDI Evaluation

This presentation will summarize the state-of-the-art in transporters in drug development based on four recent ITC3 whitepapers (Clin Pharmacol Ther 104, October 2018).  Practical overview of emerging transporters of clinical relevance will be provided (e.g., OCT1, OATP2B1, etc.).  Best practice in design of clinical DDI studies will be illustrated with recent advances in the study of OCT1, P-gp, and BCRP.  Considerations for optimal selection of clinical probe drugs, including future potential utility of transporter biomarkers, also will be discussed.
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OTHER ON-DEMAND WEBINARS

Cancer Research & Oncology 2017

labroots

LabRoots invites research professionals, scientists, and clinicians to this premier online conference, making it easier and more cost-effective to learn about recent advances in cancer research. The virtual conference is free to attendees, encouraging worldwide collaboration and connections between colleagues and field experts. Cancer research has made major advancements in diagnosis, treatments, and the basic understanding of the disease itself.
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Emerging SARS-CoV-2 Mutations webinar available on-demand

Watch these on-demand webinars to learn why Thermo Fisher Scientific is the leading single-source supplier for your COVID-19 testing needs
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Optimize This! Enhancing the Quality and Consistency of Cannabis and Extraction

Technology Networks

Everyone makes the best extracts. But are they optimized? And what does “the best” mean; does it mean high yield, high quality, or both? And what is quality anyway? Quality begins in the cultivation process and continues throughout the handling of the product from seed to sale. At OutCo, we’ve studied our production pipeline and extraction methodologies to offer optimized products to our patients. Finding the ideal balance between yield and consumer rating, we were able to optimize extraction protocols for controlled mixtures of compounds. Our custom methods enable us to create products with designer cannabinoid and terpene ratios, customized to patients’ and doctors’ needs. All of this was achieved in an efficient manner through the use of design of experiment (DoE) techniques, and continuous improvement of all processes.
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Cardiac emergencies in cardio-oncology

esc365

After watching this webinar, participants will understand: differential diagnosis of chest pain in cancer patients, including a diagnostic workup of chest pain, pericardial disease, and myocarditis; management of ACS in patients with active cancer, including a diagnostic of invasive vs. non-invasive; and antithrombotic treatment, including thrombocytopaenia and antithrombotic strategy to balance bleeding risk vs. thrombotic risk.
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