Cell and Gene Therapies

How nuclear factor-erythroid factor 2-related factor 2 (Nrf2) affects the redox status of cells, The effects of cinnamic aldehyde treatment on Nrf2, Evidence for a Nrf2-dependent mechanism of neointimal hyperplasia inhibition by cinnamic aldehyde treatment and Benefits of 3D analysis of arterial injury over traditional 2D histology analysis

Liquid biopsy, utilizing blood as a less invasive alternative for tissue samples, is becoming more and more prominent in precision medicine. The possibility to analyze blood samples across the species matrix makes mass spectrometry-based proteomics a powerful tool for early-stage, translational, and clinical research.

There are approximately 7,000 distinct rare diseases affecting 350 million people worldwide, approximately 80 percent of which are caused by faulty genes.

Because of its reliability, sensitivity and low cost, PCR has become the backbone of modern diagnostics. In recent years, researchers have ingeniously capitalized on the fundamental nature of PCR through multiplexing reactions saving reagent costs, precious samples, and user time. Multiplexing has also enabled pathogen screening and genotyping for much larger numbers of targets, thereby improving the breadth and utility of diagnostics. However, while multiplexing reactions can be a boon to lab productivity, they are not without their pitfalls.