Biology by Design: Applying Gigabases of DNA to Bioengineering

FFPE tissue samples with a low abundance of nucleic acid continue to present a challenge for cancer genomics. Such samples frequently fail to produce sufficient DNA or RNA for downstream analyses, which can impact patient care or reduce the statistical power of a study.

As gene therapies and gene-modified cell therapies show increasing promise, the need for innovative and proficient viral vector manufacturing continues to grow. Concurrently, increased regulatory guidance governing the manufacturing and testing of viral vectors adds complexity and increases the timelines to successfully produce high-quality virus ready for clinical use.

"Humanized mouse models, where human tumor tissue is engrafted into immunodeficient mouse models, are now being used in oncology and infectious disease studies to provide valuable translational insight. In this webinar, our panel of experts will discuss the successes and caveats of using humanized mouse models to understand disease biology and evaluate therapeutic strategies. Topics to be covered include the use of humanized mice to study tumor biology and to evaluate therapies for infectious disease, including HIV. Attendees will have an opportunity to interact with the experts, ask questions, and seek advice on topics that are unique to their research."

Group A Streptococcus (Group A Strep) remains fairly unchanged and is well-understood by the scientific community. However, our methods of detection have significantly improved as have various options for testing. With so many advancements in the landscape of molecular diagnostics, it is vital for all healthcare institutions to thoroughly understand and appropriately plan for common and potentially, high volume tests. In this free webinar, the featured speaker will review and explore the topic of “The Group A Strep Diagnostic Algorithm” and support a closing Q&A session. As part of his discussion, he will define and review items such as testing requirements, the disease state, prevalence in specific demographics and geographies, disease implications, the benefits and drawbacks of various testing methodologies and the testing needs of today’s variety of healthcare settings.