Basic pacemaker programming

In this webinar, Marie Piketty recalls that in recent years, several cases of interference caused by Biotin have been reported, concerning doses of thyroid hormones, but also other hormones, and other dosages. Biotin also called Vitamin B7, is a cofactor of several reactions to the carboxylase. Biotin present in multivitamin cocktails, does not present a risk of interference, but the use of Biotin at supraphysiological doses as a product of "beauty" (for hair, nails and skin), or at high doses as treatment in patients with multiple sclerosis can cause interference.

This is a fascinating, exciting, and perplexing time for biotechnology. The industry delivered RNA vaccines to save countless lives during the pandemic and has created impressive early clinical results using CRISPR gene editing to treat patients with deadly genetic diseases.

Multicellular organisms and dynamic biological processes consist of a complex and coordinated interplay of multiple individual cells. Until recently, most molecular studies have relied on bulk analysis, combining all cells into a single average readout. In recent years, single-cell RNA sequencing technologies have enabled researchers to study development and disease at the level of individual cells, revealing cell-to-cell gene expression differences that were obscured with bulk or low throughput methods.

As single-use technologies have been widely adopted by the pharmaceutical industry, there has been a corresponding shift in responsibility from end-users to suppliers.