AAV Based Gene Therapy for Rare Genetic Disorders: Strategies and Challenges

Prior to 2022, monkeypox virus was a rare cause of disease in humans with most cases being associated with travel to the continent of Africa or contact with animals from Africa. However, monkeypox is currently causing the largest outbreak in recorded history, with nearly 80,000 confirmed cases worldwide.

As it is with so many things in life, how we begin often sets the tone for the entire journey. Bioproduction endeavors are no different. Using robust reagents and developing reproducible procedures at the early stages of your bioprocess is critical to producing a safe and efficacious final product. Upstream process scientists are constantly trying to improve parameters such as growth conditions, media analysis, and optimizing cell lines to ease the burden on downstream purification steps. Determining the best way to begin your bioproduction journey takes a lot of experience and can often seem daunting. However, in this presentation, our panelists will tell us what’s necessary for those initial successful steps.

As the prevalence of diabetes continues to rise in many areas across the globe, healthcare providers continue to look for methods that will aid in the diagnosis and management of patients. This is a complex process that poses challenges for patients, physicians, hospitals and laboratories. What is changing in today’s world is that many hospitals are being asked to take steps toward improving proactive and preventive care, improving patient outcomes while also saving on healthcare costs associated with diabetes and diabetes complications. Laboratories are invaluable partners in addressing this challenge.

This event offers an overview of how live-cell analysis enables real-time analysis for the full workflow of the cells. Start at the beginning and learn more about the cell health, growth and morphology of your cells in culture. From there, gain a better understanding of the efficiency of transfection and how the consistency of cell plating as well pre-treatments can affect your cells during manipulation, all the way to the final kinetic assay itself. You’ll receive in-depth content designed to give you the tools and insights of live-cell analysis to make data driven decisions.