3D Tumor Models: Predicting Better In Vivo and Translational Results

A contamination control strategy (CCS) considers microbiological monitoring of assessed points and is a fundamental aspect of managing risks associated with contamination.

Gene engineering of immune cells has become a powerful tool for creating cellular therapies. Currently, this critical step is primarily performed using virus-based gene delivery systems.

Restaurant cleanliness matters! It’s the most important driver of customer visitation (i.e., they come back more often and increase sales) and brand loyalty, just behind the importance of employee service and food quality attributes. Employee service, “cleanliness“, and how the employee cleans are important attributes that inform a customer’s perception of good service and hospitality. Food safety management systems that control food safety hazards can also directly influence restaurant facility cleanliness, employee service, and food quality, and can be leveraged to enhance the customer experience. This session will present a successful model to enhance both food safety management and customer experience in a restaurant environment.

Cure rates for children with cancer have increased dramatically over the past 40 years with the advent of modern treatment strategies, but most patients have serious life-long medical conditions as a result of the toxicity of their treatments. Clonal hematopoiesis of indeterminate potential (CHIP) is a recently described entity that has been associated with chronic diseases, most notably coronary artery disease. To determine if the presence and features of CHIP are different in childhood cancer survivors compared to age and sex-matched controls, we performed targeted single-cell DNA sequencing of thousands of mature and progenitor hematopoietic cells from a cohort of patients that are greater than 50 years of age and received greater than 25g/m2 of highly mutagenic alkylating chemotherapy as a child.