New All of Us Genome Center to Advance Precision Medicine

HealthITAnalytics | October 21, 2019

The All of Us Research Program has selected the HudsonAlpha Institute for Biotechnology in Huntsville, Alabama to examine the use of DNA sequencing, genomics, and precision medicine for patient care. The National Center for Advancing Translational Sciences (NCATS) is funding the project, providing $7 million over the course of one year. Investigators will test cutting-edge DNA sequencing technologies that could improve diagnosis and treatment of rare and common diseases. HudsonAlpha will leverage long-read whole genome sequencing technologies to generate genetic data on about 6,000 participants from diverse backgrounds. Long-read sequencing analyzes DNA in larger segments than standard sequencing technologies and can expose genetic variations that may have otherwise gone undetected. These variations could include alterations to genetic structure, such as duplication, deletion, or rearrangement of the building blocks that make up one’s genome. Researchers are increasingly learning about how some genetic variants underlie certain health conditions or increase disease resistance. With long-read DNA sequencing, investigators will better understand the genetic underpinnings of health and disease and identify more targeted treatments in the future.

Spotlight

Earth is the only place in the universe that we know is home to life. It turns out that life can be found nearly everywhere on Earth, evolving ways to survive.

Spotlight

Earth is the only place in the universe that we know is home to life. It turns out that life can be found nearly everywhere on Earth, evolving ways to survive.

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