Aptorum Group Joins the BEAM Alliance To Combat Antimicrobial Resistance

Business Wire | September 08, 2020

Aptorum Group Limited (Nasdaq: APM, Euronext Paris: APM) (“Aptorum Group”), a biopharmaceutical company focused on novel therapeutics including the development of next-generation therapeutics targeting antimicrobial resistance, today announced it joined the Biotech companies in Europe combating Antimicrobial Resistance Alliance based in Europe (the “BEAM Alliance”) as full member. The BEAM Alliance is a network of approximately 70 small and medium-sized European companies involved in developing innovative products and kits to tackle antimicrobial resistance (“AMR”), including small molecule antibiotics, biologics, products with a prophylaxis indication, microbiome-based and phage-based therapies, immune targeting therapies, anti-biofilm agents, and medical devices, including in-vitro diagnostics.

Spotlight

Prostate Cancer is the most common type of cancer among men in Sweden as well as in many Western countries. However, approximately 85% of prostate cancer tumors are not rapidly progressing and will not cause clinical symptoms at the time of diagnosis, while the remaining 15% are more aggressive and potentially life-threatening. 

Spotlight

Prostate Cancer is the most common type of cancer among men in Sweden as well as in many Western countries. However, approximately 85% of prostate cancer tumors are not rapidly progressing and will not cause clinical symptoms at the time of diagnosis, while the remaining 15% are more aggressive and potentially life-threatening. 

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CELL AND GENE THERAPY

AgeX Therapeutics Receives Stock Exchange Deficiency Letter

AgeX Therapeutics | November 24, 2021

AgeX Therapeutics , Inc. a biotechnology company developing therapeutics for human aging and regeneration, announced that on November 17, 2021 it received a letter from the staff of the NYSE American indicating that AgeX does not meet certain of the Exchange’s continued listing standards as set forth in Section 1003(a)(i) and (ii) of the Exchange Company Guide in that AgeX has stockholders equity of less than $2,000,000 and has incurred losses from continuing operations and/or net losses during its two most recent fiscal years, and that it has stockholders equity of less than $4,000,000 and has incurred losses from continuing operations and/or net losses during three out of four of its most recent fiscal years. Pursuant to Section 1009 of the Exchange Company Guide and as provided in the Deficiency Letter, AgeX may provide the Exchange staff with a plan (the "Plan") by December 17, 2021 advising the Exchange staff of action AgeX has taken and will take that would bring AgeX into compliance with the Exchange’s continued listing standards by June 17, 2023. AgeX intends to submit a Plan by the December 17, 2021 deadline. There is no assurance that the Exchange staff will accept the Plan. If the Exchange staff accepts the Plan, the Exchange staff will review AgeX’s compliance with the Plan on a quarterly basis and if AgeX does not show progress consistent with the Plan or is not in compliance with the Exchange’s continued listing standards by June 17, 2023, the Exchange will commence delisting procedures. If AgeX does not submit the Plan or if the Exchange staff does not accept the Plan, the Exchange staff will promptly initiate delisting proceedings. AgeX intends to make arrangements to have its common stock quoted on an electronic interdealer quotation system if its common stock is delisted from the Exchange. About AgeX Therapeutics AgeX Therapeutics, Inc. is focused on developing and commercializing innovative therapeutics to treat human diseases to increase healthspan and combat the effects of aging. AgeX’s PureStem® and UniverCyte™ manufacturing and immunotolerance technologies are designed to work together to generate highly defined, universal, allogeneic, off-the-shelf pluripotent stem cell-derived young cells of any type for application in a variety of diseases with a high unmet medical need. AgeX has two preclinical cell therapy programs: AGEX-VASC1 (vascular progenitor cells) for tissue ischemia and AGEX-BAT1 (brown fat cells) for Type II diabetes. AgeX’s revolutionary longevity platform induced Tissue Regeneration (iTR™) aims to unlock cellular immortality and regenerative capacity to reverse age-related changes within tissues. HyStem® is AgeX’s delivery technology to stably engraft PureStem or other cell therapies in the body. AgeX is seeking opportunities to establish licensing and collaboration arrangements around its broad IP estate and proprietary technology platforms and therapy product candidates.

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MEDTECH

Aesthetics Biomedical® Announces Collaboration with U.S. Dermatology Partners Offering Consumers Luxury Experiential Aesthetic Treatments

Aesthetics Biomedical® Inc. | October 07, 2021

Aesthetics Biomedical® Inc. (ABM), is pleased to announce their long-term partnership with U.S. Dermatology Partners, the largest physician-led dermatology practice in the United States. With years of experience and more than 90+ locations throughout Arizona, Colorado, Kansas, Maryland, Missouri, Oklahoma, Texas, and Virginia, U.S. Dermatology Partners combines the personal level of care found in private dermatology practices with the benefits of a network of physician experts working closely together. As a result, U.S. Dermatology Partners can provide premier medical and cosmetic dermatological care, along with the latest technology, treatments, and management support. Striving to innovate, generate solid clinical and laboratory research, and to enrich the physician as well as the patient experience are principles that Aesthetics Biomedical® was founded on. It is these foundational principles that have led to our synergy with U.S. Dermatology Partners. -Chief Executive Officer & Founder, MaryAnn Guerra U.S. Dermatology Partners, a pinnacle network of specialty experts found a lifetime partner in excellence and innovation with Aesthetics Biomedical®. Beginning in 2021, U.S. Dermatology Partners installed Vivace® into four initial practices. A pilot project between the two organizations launched the partnership that resulted in over 170 consumer treatments being sold within the first four weeks. U.S. Dermatology Partners and ABM marketed the Vivace Experience® concept with the objective of delivering an immediate ROI supporting the purchase of the initial device for the organization. Vivace® is a primary driver expected to positively impact U.S. Dermatology Partners' market growth exponentially and rapidly, already generating significant revenue in six locations across the US, in under six (6) months. Having access to ongoing knowledge and clinical data is critical to U.S. Dermatology Partners physicians who are committed to continuous and consistent superior patient care. U.S. Dermatology Partners is thrilled to be collaborating with Aesthetics Biomedical® to bring the Vivace Experience® to our patients and our growing network to Aesthetics Biomedical®. We expect the innovative technology and outstanding results that Vivace offers will be well-received by both our physicians and patients and will provide another opportunity to deliver superior care to the communities we serve. - U.S. Dermatology Partners Chief Executive Officer Paul Singh Vivace® is a minimally invasive, FDA-cleared, radiofrequency microneedling treatment that stimulates the natural production of collagen and has been shown by physicians to be effective in alleviating facial wrinkles, fine lines, and tightening the face and neck. Aesthetics Biomedical's Vivace® is currently offered in multiple U.S. Dermatology Partners practices across 50% of the markets nationwide with rapid expansion plans in Q4. ABM will help to drive U.S. Dermatology Partners's practice success with superior technology, devices, and products supported by science, customer-focused market recognition, rigorous and continuing education, and strong continuous return on investment. Both organizations are aligned in their commitment to excellence and share a common goal for elevating the consumer experience at the forefront of the partnership. ABOUT AESTHETICS BIOMEDICAL Aesthetics Biomedical® Inc., headquartered in Phoenix, Ariz., is committed to the development and distribution of novel aesthetic devices, products, and services in the global market. Aesthetics Biomedical's innovation center is a leader in breakthrough technologies and combination therapies for its clients, physician network, and the aesthetic arena, creating novel patient treatment experiences that benefit from ongoing research, approved clinical indications for use, as well as a personalized approach designed for consumer benefit. ABOUT U.S. DERMATOLOGY PARTNERS As one of the largest physician-owned dermatology practices in the country, U.S. Dermatology Partners patients not only have access to general medical, surgical, and cosmetic skin treatment through its coordinated care network, but also benefit from the practice's strong dermatology subspecialty thought leaders and medical advisory board. To be the best partners to its patients, U.S. Dermatology Partners is fervently focused on providing the highest level of patient-first care, and its team, therefore, includes recognized national leaders in areas such as clinical research, psoriasis, and Mohs Surgery.

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Moleculin Announces Discovery of Significant In Vitro Activity Against SARS-CoV-2

Moleculin | September 29, 2020

Moleculin Biotech, Inc., (Nasdaq: MBRX) (Moleculin or the Company), a clinical stage pharmaceutical company with a broad portfolio of drug candidates targeting significant unmet needs in the treatment of tumors and viruses, announced that its research team has discovered that a molecule within its portfolio of antimetabolites has displayed significant in vitro antiviral activity against SARS-CoV-2. Independent laboratory testing of the new drug candidate, called "WP1096," has now repeatedly demonstrated a therapeutic index of greater than 10, which is considered by our team to be an industry-standard commercialization threshold for in vitro performance of antiviral drugs. Walter Klemp, Chairman and CEO of Moleculin, stated, "While we continue to see encouraging progress with WP1122 in preparation for clinical trials for the potential treatment of COVID-19, we have also continued our antiviral drug discovery program to expand the range of potential therapies. Our efforts led to a new discovery that we believe can be a game-changer. WP1096 and its close analog, WP1097, are structurally slightly different agents within the WP1122 portfolio. However, small structural changes unexpectedly resulted in high levels of antiviral activity and potentially a unique mode of action.

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