Antibe Therapeutics Inc. a clinical-stage company leveraging its hydrogen sulfide platform to develop next-generation safer therapies that target inflammation, is pleased to announce the selection of a poster presentation of clinical data supporting otenaproxesul’s acute pain efficacy, to be delivered at the PAINWeek National Conference taking place on September 6 - 9 in Las Vegas. The poster will be presented by the lead author of the study and Antibe academic collaborator, James R.W. Glanville, MBChB, MRCP, a UK-based rheumatologist with an academic affiliation to University College London.
“I’m delighted to have the opportunity to share our clinical data at PAINWeek. As our poster details, the study showed otenaproxesul’s remarkable potency in reducing pain and inflammation. Of particular interest was otenaproxesul’s ability to reduce white blood cell infiltration. Given the ongoing opioid crisis, it is imperative that we find novel, efficacious therapeutics that limit adverse effects and risk. As a physician focused on treating inflammatory conditions, I appreciate the potential of otenaproxesul as a GI-sparing alternative to traditional NSAIDs.”
Dr. Glanville
The poster reflects results originally published in a peer-reviewed research paper in The FASEB Journal (Federation of American Societies for Experimental Biology) available at faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fj.201902918RR. Utilizing a novel experimental model of human inflammation, the 2019 study involved 21 healthy male volunteers randomly assigned into one of three treatment arms, including a no-treatment control group. The poster will be available in the Scientific Publications section of the Company’s website following the presentation.
Dr. Joseph Stauffer, Antibe’s Chief Medical Officer, remarked, “We appreciate the pioneering work that Dr. Glanville and his colleagues have done to elucidate otenaproxesul’s acute pain efficacy in humans. With its Phase II acute pain program initiating this month, we are excited to have the drug’s first acute pain results presented to practitioners at a major conference.”
Held annually, the PAINWeek National Conference is the largest U.S. conference for frontline healthcare professionals with an interest in pain management.
About Antibe Therapeutics Inc.
Antibe is a clinical stage biotechnology company leveraging its proprietary hydrogen sulfide platform to develop next-generation safer therapies to target inflammation arising from a wide range of medical conditions. The Company’s current pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs. Antibe’s lead drug, otenaproxesul, is in clinical development as a safer alternative to opioids and today’s NSAIDs for acute pain. Antibe’s second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company’s anticipated next target is inflammatory bowel disease a condition long in need of safer, more effective therapies.