Patients living with Spinal Muscular Atrophy (SMA) in the province of Saskatchewan gain access to SPINRAZA™ (nusinersen)

| April 22, 2019

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Biogen Canada welcomes the decision made by the Government of Saskatchewan allowing patients living with Spinal Muscular Atrophy (SMA) to access SPINRAZA (nusinersen), the first and only approved medicine in the world to treat the root cause of SMA. The Saskatchewan Ministry of Health has made the decision to expand coverage and make SPINRAZA™ available to include the following, in addition to existing Type I patients: Patients who are pre-symptomatic with two or three copies of the SMN2 gene; Patients up to age 18, with symptom onset after six months of age and who have never achieved the ability to walk independently. Patients that may have achieved the ability to walk independently (type III) as well as type II and type III patients over the age of 18 are encouraged to talk to their treating physician to apply for a case by case coverage.

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Sartorius Stedim BioOutsource

Sartorius Stedim BioOutsource Ltd. (part of Sartorius Stedim Biotech Group) is one of the world’s leading providers of contract testing services to the biopharmaceutical and biotechnology industries, offering an extensive range of services to support the testing of biologic drugs and vaccines throughout development and manufacture.

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