New Feature: Biotech Business Areas

TODD SMITH | February 27, 2019 | 40 views

One of the great features of the Biotech-Careers.org website is its biotechnology employer database. In Biotech-Careers.org, biotechnology (biotech) employers are companies and other organizations that are engaged in life sciences research, develop drugs and products, or provide services. Biotech is thus defined broadly to capture the breadth and depth of the industry. This broad definition is also used because students receiving biotech education in community, and other, colleges are learning and developing skills that can be suitable for many kinds of employers. For example, anyone learning to work with and clone DNA could go on to work in organizations that utilize molecular biology in product development, develop DNA-based diagnostics, or provide DNA sequencing services.

Spotlight

Grasse BIOTECH

Grasse BIOTECH - Hotel of innovation companies and support of startups in the field of cosmetologies, biotechnologies, health, life sciences and scientific research and analysis activities of the Pays de Grasse, benefits from added value linked to a privileged project accelerator environment. On the ArômaGrasse Business Park where are hosted more than 15 companies such as: Perfume Cosmetic World, TOMCOS, SelectArôme ... mostly PASS (Perfumes, Aromas, Scents, Flavors). In connection with Espace Jacques-Louis Lions where are located: o the InnovaGrasse business incubator, o the University of Nice Sophia-Antipolis: training in fine chemistry master 2 FOQUAL, its students, professors and researchers in a place conducive to teaching and research (classrooms, laboratories, exchange rooms ...), o Technological and regulatory resources represented by the PASS Competitiveness Cluster and its partnership analytical chemistry platform, whose objective is to strengthen R & D by bringing researcher

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MEDTECH

Top 10 biotech IPOs in 2019

Article | October 7, 2022

The big question at the start of 2019 was whether the IPO window would stay open for biotech companies, particularly those seeking to pull off ever-larger IPOs at increasingly earlier stages of development. The short answer is yes—kind of. Here’s the long answer: In the words of Renaissance Capital, the IPO market had “a mostly good year.” The total number of deals fell to 159 from 192 the year before, but technology and healthcare companies were standout performers. The latter—which include biotech, medtech and diagnostics companies—led the pack, making up 43% of all IPOs in 2019. By Renaissance’s count, seven companies went public at valuations exceeding $1 billion, up from five the year before

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MEDTECH

Cell Out? Lysate-Based Expression an Option for Personalized Meds

Article | July 11, 2022

Cell-free expression (CFE) is the practice of making a protein without using a living cell. In contrast with cell line-based methods, production is achieved using a fluid containing biological components extracted from a cell, i.e., a lysate. CFE offers potential advantages for biopharma according to Philip Probert, PhD, a senior scientist at the Centre for Process Innovation in the U.K.

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MEDTECH

Closing bacterial genomes from the human gut microbiome using long-read sequencing

Article | July 16, 2022

In our lab, we focus on the impact of the gut microbiome on human health and disease. To evaluate this relationship, it’s important to understand the particular functions that different bacteria have. As bacteria are able to exchange, duplicate, and rearrange their genes in ways that directly affect their phenotypes, complete bacterial genomes assembled directly from human samples are essential to understand the strain variation and potential functions of the bacteria we host. Advances in the microbiome space have allowed for the de novo assembly of microbial genomes directly from metagenomes via short-read sequencing, assembly of reads into contigs, and binning of contigs into putative genome drafts. This is advantageous because it allows us to discover microbes without culturing them, directly from human samples and without reference databases. In the past year, there have been a number of tour de force efforts to broadly characterize the human gut microbiota through the creation of such metagenome-assembled genomes (MAGs)[1–4]. These works have produced hundreds of thousands of microbial genomes that vastly increase our understanding of the human gut. However, challenges in the assembly of short reads has limited our ability to correctly assemble repeated genomic elements and place them into genomic context. Thus, existing MAGs are often fragmented and do not include mobile genetic elements, 16S rRNA sequences, and other elements that are repeated or have high identity within and across bacterial genomes.

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Selexis Cell Line Development Strategies

Article | February 11, 2020

In today’s biotechnology landscape, to be competitive, meet regulations, and achieve market demands, “we must apply Bioprocessing 4.0,” said Igor Fisch, PhD, CEO, Selexis. In fact, in the last decade, “Selexis has evolved from cloning by limiting dilution to automated cell selection to nanofluidic chips and from monoclonality assessment by statistical calculation to proprietary bioinformatic analysis,” he added. Single-use processing systems are an expanding part of the biomanufacturing world; as such, they are a major component of Bioprocessing 4.0. “At Selexis, we use single use throughout our cell line development workflow. Currently, we have incorporated single-use automated bioprocessing systems such as ambr® and the Beacon® optofluidic platform for accelerated cell line development. By using these systems and optimizing our parameters, we were able to achieve high titers in shake flasks. Additionally, the Beacon systems integrate miniaturized cell culture with high-throughput liquid handling automation and cell imaging. This allows us to control, adjust, and monitor programs at the same time,” noted Fisch.

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Spotlight

Grasse BIOTECH

Grasse BIOTECH - Hotel of innovation companies and support of startups in the field of cosmetologies, biotechnologies, health, life sciences and scientific research and analysis activities of the Pays de Grasse, benefits from added value linked to a privileged project accelerator environment. On the ArômaGrasse Business Park where are hosted more than 15 companies such as: Perfume Cosmetic World, TOMCOS, SelectArôme ... mostly PASS (Perfumes, Aromas, Scents, Flavors). In connection with Espace Jacques-Louis Lions where are located: o the InnovaGrasse business incubator, o the University of Nice Sophia-Antipolis: training in fine chemistry master 2 FOQUAL, its students, professors and researchers in a place conducive to teaching and research (classrooms, laboratories, exchange rooms ...), o Technological and regulatory resources represented by the PASS Competitiveness Cluster and its partnership analytical chemistry platform, whose objective is to strengthen R & D by bringing researcher

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