Elephant genes suppress tumours. Could studying this help us prevent cancer?

STEVE GILLMAN | February 14, 2019

article image
The genetics and aging rate of elephants could hold clues to helping us find better ways to fight cancer and lead to healthier, longer lives. In 2015, 1.3 million people died from cancer in the EU, more than one-quarter of the total number of deaths across the 28 nations. Despite cancer treatment improving in recent years, the rate of people diagnosed is increasing, says Dr. Robin Cristofari, a biologist at the University of Turku, Finland.

Spotlight

Premier Health Care Management

Family owned and operated since 1998, Premier Health Care Management has built a reputation of quality and excellence. We deliver post-acute and long-term care to those in need and currently operate 8 buildings across Cincinnati and Dayton. Our hand-selected staff has the education and expertise you’ve come to expect from the Premier name. We feel it is a privilege to celebrate the lives of your loved ones. Here at Premier, our family is honored to care for yours.

OTHER ARTICLES
MEDICAL

Better Purification and Recovery in Bioprocessing

Article | August 2, 2021

In the downstream portion of any bioprocess, one must pick through the dross before one can seize the gold the biotherapeutic that the bioprocess was always meant to generate. Unfortunately, the dross is both voluminous and various. And the biotherapeutic gold, unlike real gold, is corruptible. That is, it can suffer structural damage and activity loss. When discarding the dross and collecting the gold, bioprocessors must be efficient and gentle. They must, to the extent possible, eliminate contaminants and organic debris while ensuring that biotherapeutics avoid aggregation-inducing stresses and retain their integrity during purification and recovery. Anything less compromises purity and reduces yield. To purify and recover biotherapeutics efficiently and gently, bioprocessors must avail themselves of the most appropriate tools and techniques. Here, we talk with several experts about which tools and techniques can help bioprocessors overcome persistent challenges. Some of these experts also touch on new approaches that can help bioprocessors address emerging challenges.

Read More
DIAGNOSTICS

Making Predictions by Digitizing Bioprocessing

Article | April 20, 2021

With advances in data analytics and machine learning, the move from descriptive and diagnostic analytics to predictive and prescriptive analytics and controls—allowing us to better forecast and understand what will happen and thus optimize process outcomes—is not only feasible but inevitable, according to Bonnie Shum, principal engineer, pharma technical innovation, technology & manufacturing sciences and technology at Genentech. “Well-trained artificial intelligence systems can help drive better decision making and how data is analyzed from drug discovery to process development and to manufacturing processes,” she says. Those advances, though, only really matter when they improve the lives of patients. That’s exactly what Shum expects. “The convergence of digital transformation and operational/processing changes will be critical for the facilities of the future and meeting the needs of our patients,” she continues. “Digital solutions may one day provide fully automated bioprocessing, eliminating manual intervention and enabling us to anticipate potential process deviations to prevent process failures, leading to real-time release and thus faster access for patients.” To turn Bioprocessing 4.0 into a production line for precision healthcare, real-time release and quickly manufacturing personalized medicines will be critical. Adding digitization and advanced analytics wherever possible will drive those improvements. In fact, many of these improvements, especially moving from descriptive to predictive bioprocessing, depend on more digitization.

Read More

Spotlight

Premier Health Care Management

Family owned and operated since 1998, Premier Health Care Management has built a reputation of quality and excellence. We deliver post-acute and long-term care to those in need and currently operate 8 buildings across Cincinnati and Dayton. Our hand-selected staff has the education and expertise you’ve come to expect from the Premier name. We feel it is a privilege to celebrate the lives of your loved ones. Here at Premier, our family is honored to care for yours.

Events