Another Pharma sloughs off Small Molecules to focus on Biologics

Over 90% of the drugs on the market today are small molecules, but the bell has been tolling for these therapies for some time now as biopharma is increasingly focused on biologics. In 2012, biologics accounted for a whopping 71% of pharma revenue, up from just 7% in 2000. Indeed, 7 of the 10 top-selling drugs in 2015 were biological, and the global market for biologics is projected to grow to €207Bn next year!

Spotlight

DBV Technologies

DBV Technologies (DBV) is a clinical-stage biopharmaceutical company focused on discovering safe and effective treatments for patients with food allergies and other unmet medical needs. DBV has developed a proprietary technology platform called Viaskin®, which is based on epicutaneous immunotherapy, or EPIT®, DBV’s method of delivering biologically active compounds to the immune system. This novel mechanism of action accesses the immune system through intact skin without allowing passage of the antigen into the bloodstream. The company is also exploring Viaskin® in other areas of unmet need including vaccines, inflammatory conditions

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Medical

Wisconsin biotech companies could play key roles in long-term economic recovery from COVID-19 pandemic

Article | August 16, 2022

Whether it’s called a modern “Manhattan Project” or a medical moon shot, the concept of long-term economic recovery rests on how confident people are they won’t risk serious illness by venturing forth in public again. Wisconsin stands to be a significant part of such an undertaking, whatever it’s called. The shorter-term debate is well under way over the gradual lifting of COVID-19 emergency rules, such as the now-extended “safer-at-home” order in Wisconsin. At least a dozen states, including regional coalitions on the East and West coasts, are exploring next steps as they seek to balance responses to the virus with calls for reopening the economy, at least, in part. Wisconsin’s ability to shape longer-term responses will come from private and public resources, which range from companies engaged in production of diagnostics.

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Medical

2022 U.S. Market Research Report with COVID-19 Forecasts2

Article | July 14, 2022

The global biotechnology market is expected to grow at a compound annual growth rate (CAGR) of 13.9 percent from 2022 to 2030, with a value estimated at USD 1,023.92 billion in 2021. The market is being propelled by strong government support in the form of initiatives aimed at modernizing the regulatory framework, improving approval processes and reimbursement policies, and standardizing clinical studies. The growing presence of personalized medicine and an increasing number of orphan drug formulations are opening up new avenues for biotechnology applications and driving the influx of emerging and innovative biotechnology companies, which is driving market revenue even further. The 2022 Biotech Research and Development Market Research Report is one of the most comprehensive and in-depth assessments of the industry in the United States, containing over 100 data sets spanning the years 2013 to 2026. This Kentley Insights report contains historical and forecasted market size, product lines, profitability, financial ratios, BCG matrix, state statistics, operating expense details, organizational breakdown, consolidation analysis, employee productivity, price inflation, pay bands for the top 20 industry jobs, trend analysis and forecasts on companies, locations, employees, payroll, and much more. Companies in the Biotech Research and Development industry are primarily engaged in biotechnology research and experimental development. Biotechnology research and development entails the investigation of the use of microorganisms and cellular and bimolecular processes to create or modify living or non-living materials. This biotechnology research and development may result in the development of new biotechnology processes or prototypes of new or genetically altered products that can be replicated, used, or implemented by various industries. This report was created using the findings of extensive business surveys and econometrics. The professionals follow reports with accurate and apt information on market sizing, benchmarking, strategic planning, due diligence, cost-cutting, planning, understanding industry dynamics, forecasting, streamlining, gap analysis, and other ana

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MedTech

5 Biotech Stocks Winning the Coronavirus Race

Article | July 16, 2022

There are quite a few companies that have found ways to grow their business during the ongoing COVID-19 pandemic. This is especially true for a number of biotechs now working on developing a potential treatment for, or vaccine against, the virus; shares of such companies have largely surged over the past couple of months. Although many of these treatments and vaccines are still have quite a way to go before they're widely available, it's still worth taking some time to look through what's going on in the COVID-19 space right now. Here are five biotech stocks that are leading the way when it comes to addressing COVID-19. Regeneron Pharmaceuticals (NASDAQ:REGN) wasn't among the initial wave of companies to announce a potential COVID-19 drug. However, investor excitement quickly sent shares surging when the company announced that its rheumatoid arthritis drug, Kevzara, could help treat COVID-19 patients.

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Medical

Better Purification and Recovery in Bioprocessing

Article | August 2, 2021

In the downstream portion of any bioprocess, one must pick through the dross before one can seize the gold the biotherapeutic that the bioprocess was always meant to generate. Unfortunately, the dross is both voluminous and various. And the biotherapeutic gold, unlike real gold, is corruptible. That is, it can suffer structural damage and activity loss. When discarding the dross and collecting the gold, bioprocessors must be efficient and gentle. They must, to the extent possible, eliminate contaminants and organic debris while ensuring that biotherapeutics avoid aggregation-inducing stresses and retain their integrity during purification and recovery. Anything less compromises purity and reduces yield. To purify and recover biotherapeutics efficiently and gently, bioprocessors must avail themselves of the most appropriate tools and techniques. Here, we talk with several experts about which tools and techniques can help bioprocessors overcome persistent challenges. Some of these experts also touch on new approaches that can help bioprocessors address emerging challenges.

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Spotlight

DBV Technologies

DBV Technologies (DBV) is a clinical-stage biopharmaceutical company focused on discovering safe and effective treatments for patients with food allergies and other unmet medical needs. DBV has developed a proprietary technology platform called Viaskin®, which is based on epicutaneous immunotherapy, or EPIT®, DBV’s method of delivering biologically active compounds to the immune system. This novel mechanism of action accesses the immune system through intact skin without allowing passage of the antigen into the bloodstream. The company is also exploring Viaskin® in other areas of unmet need including vaccines, inflammatory conditions

Related News

In historic first, FDA approves Novartis CAR-T therapy

Biopharama | August 30, 2017

The Food and Drug Administration on Wednesday approved the first CAR-T therapy, ushering in a new approach to treating cancer in a landmark decision for the rapidly advancing field of cell therapy. Treatment with the therapy, developed by Swiss pharma Novartis AG, led to remarkable results in children with an aggressive form of leukemia resistant to other drugs.

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Cancer Genetics to Buy vivoPharm for $12M

GEN | August 15, 2017

Cancer Genetics (CGI) is buying cancer drug discovery and preclinical services company vivoPharm, for $12 million in cash and shares. CGI said it expects the acquisition to strengthen its position as a provider of services for oncology discovery, in vivo and in vitro drug development, and early-phase clinical trials testing, and expand its presence in Europe and Australia. The acquisition, which has been approved by both companies’ boards, is projected to close today.

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Pfizer still mum on BD, frustrated by biosimilar market

biopharmadive | August 01, 2017

Pfizer Inc. reported second quarter earnings on Tuesday, missing analysts’ expectations for topline revenues but beating estimates on the bottom line. The company reported $4 billion in net income on $12.9 billion in revenues, missing forecasts of $13.07 billion. This miss was driven by lower sales from key drugs like Lyrica and Prevnar 13. The company’s biosimilar Inflectra continued to have mixed reimbursement — securing coverage under Medicare, but having limited success among commercial payers despite its lower cost. Pfizer priced Inflectra at a 15% discount to branded Remicade.

Read More

In historic first, FDA approves Novartis CAR-T therapy

Biopharama | August 30, 2017

The Food and Drug Administration on Wednesday approved the first CAR-T therapy, ushering in a new approach to treating cancer in a landmark decision for the rapidly advancing field of cell therapy. Treatment with the therapy, developed by Swiss pharma Novartis AG, led to remarkable results in children with an aggressive form of leukemia resistant to other drugs.

Read More

Cancer Genetics to Buy vivoPharm for $12M

GEN | August 15, 2017

Cancer Genetics (CGI) is buying cancer drug discovery and preclinical services company vivoPharm, for $12 million in cash and shares. CGI said it expects the acquisition to strengthen its position as a provider of services for oncology discovery, in vivo and in vitro drug development, and early-phase clinical trials testing, and expand its presence in Europe and Australia. The acquisition, which has been approved by both companies’ boards, is projected to close today.

Read More

Pfizer still mum on BD, frustrated by biosimilar market

biopharmadive | August 01, 2017

Pfizer Inc. reported second quarter earnings on Tuesday, missing analysts’ expectations for topline revenues but beating estimates on the bottom line. The company reported $4 billion in net income on $12.9 billion in revenues, missing forecasts of $13.07 billion. This miss was driven by lower sales from key drugs like Lyrica and Prevnar 13. The company’s biosimilar Inflectra continued to have mixed reimbursement — securing coverage under Medicare, but having limited success among commercial payers despite its lower cost. Pfizer priced Inflectra at a 15% discount to branded Remicade.

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