A Faster Way to Quantitatively Profile the Lipidome

| October 12, 2018

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The lipidome refers to the totality of lipids in cells. Lipids are one of the four major molecular components of biological organisms, along with proteins, sugars, and nucleic acids. Comparative studies of the complex lipid mixtures found in cells and tissues could potentially reveal lipid biomarkers since the presence of lipids in membranes, or as signaling molecules, is reflective of the physiological state of an organism at a given time. The lipidome covers a range of lipids from non-polar to polar. Profiling experiments often need two or more chromatography separation schemes to cover the range of polarities: a normal phase method and a reverse phase method. 

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Eleven Biotherapeutics

Eleven Biotherapeutics'​ scientists are engineering protein-based drugs using newly available structural information and the company’s unique molecular understanding of clinical effects to create the next generation of protein-based medicines to treat important diseases with unmet needs, such as inflammatory conditions and coagulation disorders.

OTHER ARTICLES

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Spotlight

Eleven Biotherapeutics

Eleven Biotherapeutics'​ scientists are engineering protein-based drugs using newly available structural information and the company’s unique molecular understanding of clinical effects to create the next generation of protein-based medicines to treat important diseases with unmet needs, such as inflammatory conditions and coagulation disorders.

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