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VISUALIZING APOPTOSIS AS IT HAPPENS

April 27, 2018

Apoptosis is a highly regulated and critical homeostatic process in multicellular organisms. Aberrations in this form of programmed cell death have been implicated in several pathological conditions including cancer, muscular atrophy, and autoimmune disease. The biochemical and morphological events underlying apoptosis include perturbations in mitochondrial membrane potential, death receptors on the cell surface, recruitment of adapter proteins, caspase activation, and condensation of chromatin along with nuclear fragmentation.

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