Finding High Producing Clones with Monoclonality Assurance in One Day

December 21, 2018

In the discovery and development of novel biopharmaceuticals (such as antibodies) for therapeutic use Cell Line Development is an integral process in the biomanufacturing of therapeutic proteins. Mammalian cells make ideal factories for protein production as they have similar molecular mechanisms to human cells for protein modifications such as glycosylation.

Spotlight

Bharat Serums and Vaccines Limited

Bharat Serums And Vaccines Limited is one of the fastest growing bio pharmaceutical companies in India. BSV established in 1971 by the late Dr. Vinod Daftary researches, develops, manufactures, and markets injectable biological, pharmaceutical, and biotechnology products. BSV's products portfolio includes plasma derivatives, monoclonals, fertility hormones, antifungals, anaesthetics, cardiovascular drugs, and equine immunoglobulin /antitoxins. The R&D of drug delivery systems, biotechnology/recombinant therapeutics, and biological/equine products; In addition, BSV offers products in the areas of gynaecology, assisted reproductive technology, critical care, emergency medicine, neurology, nephrology, haematology, and urology.

OTHER WHITEPAPERS
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BIOTECHNOLOGY INNOVATION ORGANIZATION

whitePaper | January 4, 2022

The Biotechnology Innovation Organization (BIO) appreciates the opportunity to participate in the 2022 Special 301 Review: Identification of Countries under Section 182 of the Trade Act of 1974: Request for Public Comment and Announcement of Public Hearing.

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Advancing Diversity in Clinical Development through Cross-Stakeholder Commitment and Action

whitePaper | November 10, 2022

The call for achieving representative diversity in clinical trials and development programs is not new and indeed dates back more than five decades in the United States but has been amplified over the course of the COVID-19

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Are Nitrosamines aConcern for BiologicManufacturers?

whitePaper | July 12, 2023

The discovery of nitrosamine genotoxins in several pharmaceuticals has led to monitoring and re-evaluation of manufacturing practices for those products considered atrisk. This article provides an assessment of nitrosamine contamination specifically in biologics and contrasts the potential risks between these product types.

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Scalable Rubella production in scale-X™ bioreactor with MRC-5 cells

whitePaper | November 18, 2022

Due to vaccine delivery gap for Rubella disease, global immunization is still limited in some parts of the world. In this paper we will demonstrate how one scale-X™ carbo fixed-bed bioreactor system.

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Characterization and identification of glucuronide metabolites

whitePaper | April 21, 2023

This technical note demonstrates the comprehensive characterization and confident identification of glucuronide metabolites from hepatocyte incubations of midazolam. An orthogonal fragmentation mechanism was applied to generate diagnostic fragmentions for confident identification of glucuronide metabolites

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Further Discussion on Plasmids to Establish Release Specifications Using a Risk-Based Approach to Manage Supply

whitePaper | December 6, 2022

BioPhorum’s mission is to create environments where the global biopharmaceutical industry can collaborate and accelerate its rate of progress, for the benefit of all.

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Spotlight

Bharat Serums and Vaccines Limited

Bharat Serums And Vaccines Limited is one of the fastest growing bio pharmaceutical companies in India. BSV established in 1971 by the late Dr. Vinod Daftary researches, develops, manufactures, and markets injectable biological, pharmaceutical, and biotechnology products. BSV's products portfolio includes plasma derivatives, monoclonals, fertility hormones, antifungals, anaesthetics, cardiovascular drugs, and equine immunoglobulin /antitoxins. The R&D of drug delivery systems, biotechnology/recombinant therapeutics, and biological/equine products; In addition, BSV offers products in the areas of gynaecology, assisted reproductive technology, critical care, emergency medicine, neurology, nephrology, haematology, and urology.

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