An introduction to Next-Generation Sequencing Technology

September 7, 2017

DNAsequencinghascome a long way since the days of two-dimensional chromatography in the 1970s. With the advent of the anger chain termination method1 in1977, scientists gained the ability tosequenceDNAin a reliable, reproducible manner. A decade later, Applied Biosystems introduced the first automated, capillary electrophoresis (CE)-based sequencing instruments, the AB370in1987and theAB3730xl in1998, instruments that became the primary workhorse for the NIH-led and Celera-led Human Genome Projects.

Spotlight

Healthcare Management Solutions Ltd

Centrally based just south of Birmingham, HCMS has a nationwide team of Regional Managers, all of whom have had multi-site management experience and therefore have both practical experience and knowledge of day to day care home operation. We operate the lowest ratios of homes to Regional Managers in the industry recognising the intensive nature of the service that we offer.

OTHER WHITEPAPERS
news image

The affordability hurdle for gene therapies

whitePaper | October 12, 2022

Advanced therapy medicinal products cell and gene therapies offer tremendous hope for patients either by actually curing serious diseases or by alleviating suffering.

Read More
news image

Establishment of the basidiomycete Fomes fomentarius for the production of composite materials

whitePaper | February 24, 2022

Filamentous fungi of the phylum Basidiomycota are considered as an attractive source for the biotech‑ nological production of composite materials. The ability of many basidiomycetes to accept residual lignocellulosic plant biomass from agriculture and forestry.

Read More
news image

Leveraging innovations in plasmid manufacturing to bring advanced therapies to market

whitePaper | December 13, 2022

The global demand for plasmid DNA has increased dramatically in recent years, fueled by a surge in the clinical development of next-generation cell and gene therapy products and more recently by the success of COVID-19 vaccines.

Read More
news image

Next-Generation Technology, Procedures, and Products Facilitate Biopreservation Best Practices for Cellular Therapies.

whitePaper | August 19, 2022

The quality of procedures and products used for preparing, transporting and storing cells at cryogenic temperatures have a direct impact on post-thaw viability and functionality, as well as the consistency and reliability of biological agents from a Quality perspective.

Read More
news image

Early engagement and regulatory considerations for biotech

whitePaper | March 24, 2023

Biotechnology companies are at the epicenter of innovative drug development, with discoveries spanning from small molecules, large molecules, and biologics to genomic medicines and first-inclass immunotherapies.

Read More
news image

Healthcare system readiness for the adoption of advanced therapies: learnings from the introduction of CAR T cell therapies in the UK

whitePaper | September 17, 2021

The adoption of CAR T therapies in the UK NHS is a success story, especially seen in relation to the experience in many other countries. The UK NHS showed itself to be agile, and responsive to addressing the unique challenges these therapies present, which facilitated access to patients earlier than in many other countries. (including delivery centre selection, development of service specifications, collaboration with manufacturers throughout the preparation phase for adoption, establishment of national multidisciplinary CAR T team to ensure equity of access and prioritization of resources (where needed)).

Read More

Spotlight

Healthcare Management Solutions Ltd

Centrally based just south of Birmingham, HCMS has a nationwide team of Regional Managers, all of whom have had multi-site management experience and therefore have both practical experience and knowledge of day to day care home operation. We operate the lowest ratios of homes to Regional Managers in the industry recognising the intensive nature of the service that we offer.

Events