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What Do We Know About the Gut Microbiota in Parkinson’s Disease?

November 12, 2019 / Technology Networks

Since the discovery that the gut microbiome may play a role in the development of Parkinson's disease (PD), this fresh scientific approach has produced varying results. In this review published in the Journal of Parkinson's Disease scientists compare results of current research and provide recommendations to increase the comparability and utility of these studies with a view towards improving patient outcomes. “Despite the large societal impact of PD, the underlying cause remains elusive and only symptomatic treatments exist,” explained Filip Scheperjans, lead author of the review and chief investigator of the study that first identified gut microbiome differences in PD. “Since our study appeared in 2015, 15 human case-control studies with original data have found changes in the gut microbiome composition of PD patients, but their results vary. The challenge is to identify whether these changes are actually relevant for PD patients and whether they play a role...