The need for a better understanding of the mechanisms that drive obesity and diabetes has never been more apparent. Changes in average body mass index (BMI) calculations, from 1975 to 2014 in 200 countries across the globe, were recently compiled by the NCD Risk Factor Collaboration and published in the Lancet. The authors calculated a steady increase in the average global BMI in both women and Page 4 of 17 men, from approximately 21.9 kg/m2 in 1975 to 24.3 kg/m2 in 2014.