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HOW TO OVERCOME THE CHALLENGES OF 3D AUTOMATED CELLULAR IMAGE-BASED SCREENING

January 30, 2020 | (11:00 AM)
USA (United States of America)
SHARESHARESHARE
There is an accelerating trend in biomedical research and drug discovery to improve on the standard methods of in vitro cell culture. Cells cultured on a 2D surface provide great access for studying biological processes, introducing environmental or genetic perturbations, and quantifying a cellular response. However, the micro-environment of these cells differs greatly from the complex and highly organized 3D environment found in vivo. Recent studies have shown cells behave differently when cultured in a more physiologically relevant environment that closely mimics the functional and morphological properties of organs and tissues. These 3D models are believed to be more predictive of true cell behavior in humans. In this webinar, we’ll address the challenges faced when imaging 3D cultures in a high-throughput setting