BioAgilytix | August 17, 2021
BioAgilytix Labs,a leading global contract research laboratory focused on supporting its pharmaceutical and biotech partners in all stages of large molecule drug development, announced today that it signed a definitive agreement to purchase 360biolabs®, the most comprehensive contract research organization in Australia. The transaction will expand BioAgilytix's global footprint into a jurisdiction of choice to commence first-in-human trials (FIH) and early-phase clinical trials and adds further capacity by joining 360biolabs' internationally recognised Quality systems in Melbourne, Victoria with BioAgilytix's existing laboratories in Durham, North Carolina; Boston, Massachusetts; and Hamburg, Germany.
Located in Australia's biomedical and clinical research hub, 360biolabs offers world-class virology and immunology expertise, with BSL 2 and 3 laboratories, biomarker and immune monitoring capabilities with a state-of-the-art flow cytometry suite, molecular biology PCR suite and expansive bioanalytical LC-MS/MS small molecule capabilities.
"This planned acquisition is part of our strategic growth strategy to expand our capacity, expertise and agility to serve customers across all geographies, and we look forward to welcoming the 360biolabs team and integrating the business," said Jim Datin, President and CEO of BioAgilytix. "Joining forces makes sense for our two organizations, but most importantly for our combined clients and the patients they serve. BioAgilytix and 360biolabs are already culturally aligned in our focus on doing science right, on time, the first time. Together, we will not only create significant scientific synergies but also generate new innovations and help bring future life-changing therapeutics to patients more rapidly around the globe."
"From the launch of 360biolabs in 2015, our strategic vision was to build a global speciality laboratory, providing support to enable future medicines for human health," said Angela Luttick, 360biolabs Cofounder and Executive Vice President, Business Development. Added 360biolabs Cofounder and CEO Alistair Draffan, "Finding a like-minded partner, driven by a team-focused culture of excellence with an international reputation, US and European presence, will drive our strategic expansion and support our clients' clinical development programs." Melinda Pryor, Cofounder and Executive Vice President, Clinical stated, "We're excited to join forces with the BioAgilytix team, a company that shares our strong scientific track record and commitment to quality and service. Together, we have the capabilities and capacity to meet all challenges, especially in this time of pandemic, and create enduring opportunities for a brighter future."
The Burnet Institute, a global medical research and public health organisation, is a Cofounder and majority shareholder of 360biolabs. Burnet Institute Director and CEO, Professor Brendan Crabb AC said, "Burnet Institute is proud of its involvement in the foundation of 360biolabs. It is the right time, with the growing need for high quality clinical trial support, for a company of the scale, capability, and reputation of 360biolabs to join with BioAgilytix and expand their capacity to service their customers and facilitate high quality translational medical research."
The acquisition is subject to Australian Foreign Investment Review Board ("FIRB") requirements and, subject to receipt of FIRB approval, is expected to close in the third quarter of 2021. BioAgilytix selected White & Case as legal counsel to oversee the closing of the acquisition, with Lazard Australia and Allens representing 360biolabs.
BioAgilytix is a leading bioanalytical testing laboratory specializing in large molecule bioanalysis. With laboratory locations in North Carolina's Research Triangle Park, the Cambridge area of Massachusetts, and Hamburg, Germany, BioAgilytix provides PK, immunogenicity, biomarkers, and cell-based assay services supporting the development and release testing of biologics across a number of industries and disease states. BioAgilytix offers assay development, validation, and sample analysis under non-GLP, GLP, and GCP, as well as GMP quality control testing (i.e., product release testing, stability testing, etc.). BioAgilytix also offers diagnostic testing services at its CLIA-certified, CAP-accredited Boston laboratory.
360biolabs® is the leading and most comprehensive specialty laboratory in the Australia & New Zealand region. Our expert pharmacokinetic (PK) and pharmacodynamic (PD) assay services support small molecule, biologic, vaccine and other innovative therapeutic solutions to human health. A world class and industry experienced technical team, known for their ability to successfully deliver technically challenging assays, 360biolabs® supports global Pharmaceutical and biotech companies in a diverse and growing range of therapeutics areas.
Ligand Pharmaceuticals | July 29, 2021
Landing AI announced today that it has entered into a software licensing deal with Ligand Pharmaceuticals Incorporated to integrate LandingLens into Ligand's OmniAb and xPloration antibody discovery platforms. LandingLens is a software platform that offers an end-to-end process for developing, experimenting and delivering AI-powered visual inspection solutions.
The new AI-powered tools enhance Ligand's high-throughput single B cell screening accuracy and throughput in a wide range of complex biological assays, possibly increasing the output of antibodies with desired characteristics in less time.
"Landing AI, led by world-renowned AI pioneer Andrew Ng, is a proven and trusted partner in enabling their clients to achieve the business value of computer vision," says Bob Chen, Ph.D., Ligand Pharmaceuticals' Director, Systems Engineering. "We selected Landing AI because of its unique data-centric approach, which puts collecting high-quality data at the core of AI development. Notably, the LandingLens software platform includes plenty of data preparation tools and features that enable us to create reliable and consistent datasets that we can iterate on over time to improve our existing AI systems continuously."
"Deep learning and AI have emerged as strong technologies for enabling a wide range of vision-based applications. We are happy to be working with Ligand Pharmaceuticals and are dedicated to providing the best tools to assist our customers in unlocking the promise of AI, "said John Reuter, Landing AI's Vice President of Sales.
About Ligand Pharmaceuticals
Ligand is a revenue-generating biopharmaceutical company that focuses on creating or acquiring technologies that aid pharmaceutical companies in discovering new medicines. Ligand's business strategy adds value to stockholders by offering a diverse portfolio of biotech and pharmaceutical product revenue streams backed by an efficient and low corporate cost structure. Ligand's goal is to provide investors with the chance to participate in the biotech industry's promise through a profitable, diversified, and lower-risk business than a typical biotech firm. Ligand's business strategy is built on what the company specializes in drug discovery, early-stage drug development, product reformulation, and partnering. In addition, Ligand collaborates with other pharmaceutical firms to capitalize on their capabilities (late-stage development, regulatory management, and commercialization) to generate revenue.
About AI Landing
Using enablement tools, Landing AI enables clients to realize the business and operational benefits of computer vision. LandingLens, the company's main product, is an enterprise MLOps system that enables end-to-end processes for developing, iterating, and deploying AI-powered visual inspection solutions. As data quality is important to the achievement of production AI systems, LandingLens includes plenty of specially designed data preparation tools and processes to assist users in achieving optimum data accuracy and consistency. Dr. Andrew Ng, the co-founder of Coursera, former chief scientist of Baidu, and founding lead of Google Brain, founded Landing AI, guided by a data-centric AI approach, and is uniquely positioned to help companies successfully move their AI projects from proof-of-concept to full-scale production.
Omega Therapeutics, Inc | October 14, 2021
Omega Therapeutics, Inc. ("Omega"), a development-stage biotechnology company pioneering the first systematic approach to use mRNA therapeutics as programmable epigenetic medicines by leveraging its OMEGA Epigenomic Programing™ platform, today announced a strategic research collaboration with researchers at the Stanford University School of Medicine to explore the therapeutic potential of Omega Epigenomic Controllers (OECs) to control ocular disease genes associated with inflammation or regeneration of ocular tissues.
Under the terms of the collaboration, Omega and members of the Ophthalmology Department of Stanford University School of Medicine will use the OMEGA Epigenomic Programming platform to discover and research novel ocular targets for potential future OEC development candidates. Albert Wu, M.D., Ph.D., FACS, Associate Professor of Ophthalmology, will serve as principal investigator. Other contributors will include Jeffrey Goldberg, M.D., Ph.D., Professor and Chair of Ophthalmology, and Michael Kapiloff, M.D., Ph.D., Associate Professor (Research) of Ophthalmology.
"Through this research collaboration, we aim to expand the reach of our OMEGA platform within regenerative medicine, immunology, and inflammation with ocular disease targets. We will continue exploration of the broad potential of our disruptive platform and OECs, our new class of mRNA therapeutics as programmable epigenetic medicines."
Mahesh Karande, President and Chief Executive Officer of Omega Therapeutics
About Omega Therapeutics
Omega Therapeutics is a development-stage biotechnology company pioneering the first systematic approach to use mRNA therapeutics as programmable epigenetic medicines by leveraging its OMEGA Epigenomic Programming™ platform. The OMEGA platform harnesses the power of epigenetics, the mechanism that controls gene expression and every aspect of an organism's life from cell genesis, growth and differentiation to cell death. The OMEGA platform enables control of fundamental epigenetic processes to correct the root cause of disease by returning aberrant gene expression to a normal range without altering native nucleic acid sequences. Omega's engineered, modular, and programmable mRNA-encoded epigenetic medicines, Omega Epigenomic Controllers™, target specific intervention points amongst the thousands of mapped and validated novel DNA-sequence-based epigenomic loci to durably tune single or multiple genes to treat and cure disease through Precision Genomic Control™. Omega is currently advancing a broad pipeline of development candidates spanning a range of disease areas, including oncology, regenerative medicine, multigenic diseases including immunology, and select monogenic diseases.