Researchers discover cell mechanism that delays and repairs DNA damage that can lead to cancer

Phys.org | February 28, 2019

Researchers from the University of Copenhagen have identified a specific mechanism that protects cells from natural DNA errors that could permanently damage the genetic code and lead to diseases such as cancer. The study has just been published in one of the most influential scientific journals, Nature Cell Biology. Researchers from the University of Copenhagen have discovered a mechanism that gives human cells a chance to stop piling up mutations. The discovery could prove to be very useful in the development of new treatments against diseases caused by changes in human DNA such as cancer. To limit harmful changes in the genetic code that may lead to potential diseases, cells rely on a natural defense mechanism. The new study shows that specialized proteins engulf and protect the damaged DNA and 'escort' it until the damage can be repaired. The researchers discovered that this process relies on precise timing and meticulous control inside the cells.

Spotlight

Microbial fermentations are used for the production of a wide variety of products including biopharmaceuticals, enzymes, amino acids and antibiotics. Contaminations caused by bacteria or phage can have a significant financial impact upon manufacturers as fermentation raw materials must be replaced, additional downtime for root cause analysis incurred and delays to the production schedule diminish facility productivity.

Spotlight

Microbial fermentations are used for the production of a wide variety of products including biopharmaceuticals, enzymes, amino acids and antibiotics. Contaminations caused by bacteria or phage can have a significant financial impact upon manufacturers as fermentation raw materials must be replaced, additional downtime for root cause analysis incurred and delays to the production schedule diminish facility productivity.

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Rapid Reshore & Development and BrainStorm Cell Therapeutics Announce Agreement to Advance Construction of BrainStorm's U.S. Manufacturing Facilit

BrainStorm Cell Therapeutics | October 26, 2020

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Tevogen Bio™ Further Strengthens IP Portfolio With Additional Patent for Method of Preparing Its Investigational SARS-CoV-2 Specific T cell Therapy

Tevogen Bio | January 13, 2022

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