Probiotic bacteria evolve inside mice's GI tracts

Phys.org | March 26, 2019

Probiotics which are living bacteria taken to promote digestive health can evolve once inside the body and have the potential to become less effective and sometimes even harmful, according to a new study from Washington University School of Medicine in St. Louis. Researchers studying a strain of Escherichia coli (E. coli) bacteria sold in Europe as an anti-diarrheal probiotic found that the bacteria's DNA changed and they developed new capabilities after living in mice's intestines for a few weeks. Under some conditions, the probiotics even turned on their hosts and acquired the ability to eat the protective coating on the intestine. Destruction of this layer has been linked to irritable bowel syndrome. The mice's diets and the make-up of their gut bacterial community influenced how much the probiotic evolved and in what ways.

Spotlight

It is PIA-PR's Mission to foster an environment that strengthens Puerto Rico's pharmaceutical and biotechnology industry's global competitiveness and improve access to innovative medicines for its citizens. Pharmaceutical Industry Association of Puerto Rico. mprove competitiveness to retain and attract operations to Puerto Rico. Improve Patient Outcomes / Healthcare Sustainability Initiative / Build Social Capital / Build Strong Networks with Key Stakeholders / Strengthen PIA's Position and Capabilities.

Spotlight

It is PIA-PR's Mission to foster an environment that strengthens Puerto Rico's pharmaceutical and biotechnology industry's global competitiveness and improve access to innovative medicines for its citizens. Pharmaceutical Industry Association of Puerto Rico. mprove competitiveness to retain and attract operations to Puerto Rico. Improve Patient Outcomes / Healthcare Sustainability Initiative / Build Social Capital / Build Strong Networks with Key Stakeholders / Strengthen PIA's Position and Capabilities.

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Valneva SE, IDT Biologika | November 30, 2021

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Spotlight Therapeutics Raises $36.5 Million Series B to Advance a Pipeline of Cell-Targeted In Vivo CRISPR Gene Editing Biologics

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