Iterum Therapeutics Reels from Antibiotic Phase III Fail

Labiotech.eu | December 12, 2019

An antibiotic candidate developed by the Irish company Iterum Therapeutics has failed to meet the main goal of a phase III trial, a blow for efforts to meet the challenge of global antibiotic resistance. Iterum Therapeutics’ drug sulopenem was tested in a phase III trial that recruited 674 patients suffering from complicated intra-abdominal infections. These are the second most deadly type of infection for patients in intensive care. The aim of the trial was to show that sulopenem was as good at treating the infections as ertapenem, an approved antibiotic for the condition. According to the trial results, sulopenem treated the infection in almost 5% fewer patients than ertapenem. The drug statistically failed to show that it was as good as its approved counterpart.

Spotlight

The arrival of a new baby is usually a happy event, but it can also be stressful with all the new responsibilities of taking care of a new baby while dealing with the physical and hormonal changes of childbirth. 80% of new mom suffer from the baby blues which is a normal, short-lived period of feeling sad, weepy, or moody that is triggered by hormonal changes after giving birth. However, for 1 out of 7 women these mood swings are more intense and may lead to postpartum depression (PPD). Postpartum Depression is moderate to severe depression. Symptoms include tearfulness, anxiety, mood fluctuations, and irritability and may appear during pregnancy and up to one year after childbirth.  Many women are undiagnosed and are not getting the support they need. Increasing postpartum education and support will help many who are suffering alone. Here are some facts and numbers about PPD.

Spotlight

The arrival of a new baby is usually a happy event, but it can also be stressful with all the new responsibilities of taking care of a new baby while dealing with the physical and hormonal changes of childbirth. 80% of new mom suffer from the baby blues which is a normal, short-lived period of feeling sad, weepy, or moody that is triggered by hormonal changes after giving birth. However, for 1 out of 7 women these mood swings are more intense and may lead to postpartum depression (PPD). Postpartum Depression is moderate to severe depression. Symptoms include tearfulness, anxiety, mood fluctuations, and irritability and may appear during pregnancy and up to one year after childbirth.  Many women are undiagnosed and are not getting the support they need. Increasing postpartum education and support will help many who are suffering alone. Here are some facts and numbers about PPD.

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Moleculin Announces Discovery of Significant In Vitro Activity Against SARS-CoV-2

Moleculin | September 29, 2020

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Yufan Biotechnologies and Abound Bio Sign Multi-Year Agreement to Develop Next Generation CAR T-cell Therapies for Cancer

Yufan Biotechnologies | September 17, 2020

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I-Mab | July 12, 2021

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