Gilead Expands Galapagos Stake, Filgotinib Role, Pipeline Access in 5.1B Dollars R and D Collaboration

Genengnews | July 15, 2019

Gilead Sciences will shell out 5.1 billion dollars to nearly double its minority stake in Galapagos from approximately 12.3% to at least 22% and possibly about 30% through a 10-year global R and D collaboration in which Gilead will expand its role in the companies arthritis candidate filgotinib and co-develop the rest of Galapagos pipeline. “Gilead also gains exclusive access to all current and future compounds in Galapagos’ rich pipeline while Galapagos is able to expand its research activities and build commercial infrastructure,” Gilead Chairman and CEO Daniel O’Day said yesterday in a statement. Galapagos’ pipeline includes six molecules currently in clinical trials, more than 20 preclinical programs, and a drug discovery platform designed to discover and verify novel targets by using disease-related, human primary cell-based assays. In the first major R&D deal under O’Day, who took the company’s helm on March 1, Gilead agreed to pay Galapagos an eye-popping $3.95 billion upfront—more than 12 times the €318 million ($358 million) in revenue generated by Galapagos last year, and 18% of Gilead’s total $22.127 billion in 2018 revenue. Gilead will also make a $1.12 billion equity investment in Galapagos, which will use the proceeds to expand and accelerate its R&D programs, the companies said. The equity investment will consist of a subscription for new Galapagos shares at a price of €140.59 ($158.42) per share, representing a 20% premium to Galapagos’ 30-day, volume-weighted average price.

Spotlight

Microorganisms are the most abundant and diverse forms of life on Earth, with an estimated 1 trillion species. They are essential components of all ecosystems and play a crucial role in health, disease and many industrial processes. The field of microbiology has seen the enormous impact of sequencing technologies. Traditionally, microorganisms have been studied through the culturing of individual species or strains using artificial culture media; however, of the 10 million species so far cataloged, only 10,000 (0.1%) have been cultured in the laboratory. 

Spotlight

Microorganisms are the most abundant and diverse forms of life on Earth, with an estimated 1 trillion species. They are essential components of all ecosystems and play a crucial role in health, disease and many industrial processes. The field of microbiology has seen the enormous impact of sequencing technologies. Traditionally, microorganisms have been studied through the culturing of individual species or strains using artificial culture media; however, of the 10 million species so far cataloged, only 10,000 (0.1%) have been cultured in the laboratory. 

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DIAGNOSTICS

GRAIL Announces Strategic Collaboration With AstraZeneca to Develop Companion Diagnostic Tests to Enable the Treatment of Early-Stage Cancer

GRAIL | June 06, 2022

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MEDICAL

Pfizer and BioNTech Begin Rolling Submission of Biologics License Application for FDA Approval of COVID-19 Vaccine in the U.S

Pfizer, BioNTech | May 10, 2021

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CELL AND GENE THERAPY

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Kite, Shoreline Biosciences | June 18, 2021

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