Experimental HIV vaccine induces bnAb production in models

Drug Target Review | November 21, 2019

An experimental HIV vaccine has shown success in pre-clinical trials by inducing antibody production which neutralises a wide range of HIV strains. The study was conducted at Scripps Research, US, in collaboration with non-profit vaccine research organisation IAVI. The researchers demonstrated that the vaccine was able to elicit broadly neutralising antibodies (bnAbs) in rabbits, which targeted at least two critical sites on the virus. The bnAbs are able to work against HIV as they bind to sites that vary little from strain to strain. It is considered by most researchers that bnAbs need to neutralise multiple sites on HIV to provide robust protection. Although patients with HIV can produce bnAbs as part of their antibody response, this can often be infrequent and after the infection has long been established. Therefore, vaccine designs for HIV have revolved around ways to stimulate the immune system into making bnAbs.

Spotlight

Hospital and health system executives are developing and implementing new tactics to meet the healthcare industry’s core strategic need: a higher value of care at lower cost. This objective has been aided by advanced technological solutions in medical-grade  remote patient monitoring (RPM) and consumer-grade devices and apps that track a wide variety of factors including biometric indicators, activity, sleep, moods, and emergency response

Spotlight

Hospital and health system executives are developing and implementing new tactics to meet the healthcare industry’s core strategic need: a higher value of care at lower cost. This objective has been aided by advanced technological solutions in medical-grade  remote patient monitoring (RPM) and consumer-grade devices and apps that track a wide variety of factors including biometric indicators, activity, sleep, moods, and emergency response

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N2 Biomedical | September 20, 2021

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Absci | October 23, 2021

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The information that we post on these websites could be deemed to be material information. As a result, investors, the media, and others interested in Absci are encouraged to review this information on a regular basis. The contents of our website, or any other website that may be accessed from our website, shall not be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended. Absci Forward-Looking Statements Certain statements in this press release that are not historical facts are considered forward-looking within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, including statements containing the words “will,” “may,” "pursues," “anticipates,” “plans,” “believes,” “forecast,” “estimates,” “expects,” and “intends,” or similar expressions. We intend these forward-looking statements, including statements regarding drug development efforts, to be covered by the safe harbor provisions for forward-looking statements contained in Section 27A of the Securities Act and Section 21E of the Securities Exchange Act, and we make this statement for purposes of complying with those safe harbor provisions. These forward-looking statements reflect our current views about our plans, intentions, expectations, strategies, and prospects, which are based on the information currently available to us and on assumptions we have made. We can give no assurance that the plans, intentions, expectations, or strategies will be attained or achieved, and, furthermore, actual results may differ materially from those described in the forward-looking statements and will be affected by a variety of risks and factors that are beyond our control, including, without limitation, risks and uncertainties relating to drug development efforts; along with those risks set forth in our Quarterly Report on Form 10-Q filed with the U.S. Securities and Exchange Commission on September 7, 2021, as well as discussions of potential risks, uncertainties, and other important factors in our subsequent filings with the U.S. Securities and Exchange Commission. Except as required by law, we assume no obligation to update publicly any forward-looking statements, whether as a result of new information, future events, or otherwise.

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Aegle Therapeutics Receives Rare Pediatric Disease Designation from the FDA for AGLE-102 for Patients with Dystrophic Epidermolysis Bullosa

Aegle Therapeutics | October 06, 2020

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