Cleaning up the clutter: How proto-biology arose from the prebiotic clutter

Phys.org | February 06, 2019

Just like the mythical creation stories that depict the formation of the world as the story of order from chaos, the early Earth was home to a chaotic clutter of organic molecules from which, somehow, more complex biological structures such as RNA and DNA emerged. There was no guiding hand to dictate how the molecules within that prebiotic clutter should interact to form life. Yet, had those molecules just interacted randomly then, in all likelihood, that they would never have chanced upon the right interactions to ultimately lead to life. "The question is, out of all the random possibilities, are there any rules that govern these interactions?" asks Ramanarayanan Krishnamurthy, an organic chemist at the Scripps Research Institute in California.
These rules would be selective, inevitably leading to the right interactions for assembling life's building blocks. To unlock the secrets of these rules and how the prebiotic clutter transitioned to the biologically ordered world of life, Krishnamurthy utilizes a discipline called "systems chemistry," and published a paper concerning the topic in the journal Accounts of Chemical Research that explores this relatively new way of understanding how life came from non-life.

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At Fisher BioServices, we specialize in the management of critical biological materials in support for the advancement of cell therapy, high value biologics, and population-based public health research. Our state-of-the-art infrastructure allows us to develop storage configurations for a multitude of biologics and ensure our clients’ material is properly managed. We provide customized end-to-end chain of custody solutions for our large pharmaceutical clients and partners in academia and government, ensuring the integrity and efficacy of their valued material from the manufacturer to the bedside.

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Orion Biotechnology and Peptilogics Enter Strategic Research Collaboration to Enable AI-Driven Drug Discovery Against Undrugged GPCR Target

Orion Biotechnology | July 15, 2022

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Biocytogen and LiberoThera Achieve Milestone Progress in Co-Development of Fully Human GPCR Antibody Drugs

Biocytogen | July 21, 2022

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Anthos Therapeutics Announces that Abelacimab has Received FDA Fast Track Designation for the Treatment of Thrombosis Associated with Cancer

Anthos Therapeutics | July 11, 2022

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