Bolder BioTechnology Announces Positive Preclinical Data for Use of BBT-032 to Inhibit Growth of the SARS-CoV-2 Virus

PR Newswire | August 26, 2020

Bolder BioTechnology, Inc. announced today that preclinical studies have shown that its proprietary long-acting interferon beta analog, BBT-032, strongly inhibits growth of the SARS-CoV-2 virus in culture at concentrations expected to be readily achievable in patients. SARS-CoV-2 is the coronavirus responsible for the Covid-19 pandemic. Based upon these promising results, Bolder BioTechnology intends to file an Investigational New Drug Application with the U.S. Food and Drug Administration to begin testing BBT-032 in humans. BBT-032 may prove useful for accelerating clearance of the SARS-CoV-2 virus in infected patients and for preventing infections in uninfected individuals. Interferon beta is a critical component of the host innate immune system that provides broad-based protection against viruses by stimulating a patient's cells to make proteins and other molecules that allow the cells to resist infection by viruses.  By stimulating host innate immunity, BBT-032 has the potential to be an effective treatment not only against SARS-CoV-2, but also against other coronaviruses such as SARS-CoV and MERS-CoV, and future viral pandemic threats.

Spotlight

Jessica Garcia Fernandez describes her experiences of the UCD MSc Biotechnology programme, including her reasons for taking this course, the modules she studied and her research project.

Spotlight

Jessica Garcia Fernandez describes her experiences of the UCD MSc Biotechnology programme, including her reasons for taking this course, the modules she studied and her research project.

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MEDTECH

Precision Coating Announces Merger with N2 Biomedical to Expand Medical Coatings Platform

N2 Biomedical | September 20, 2021

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INDUSTRIAL IMPACT

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BioDuro-Sundia | November 09, 2021

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