ASCO: AstraZeneca's Baselga on tailoring treatments and the march to cure cancer

fiercebiotech | June 04, 2019

AstraZeneca posted promising data for its AKT inhibitor capivasertib paired with the chemotherapy Faslodex in patients with ER-positive breast cancer. The combo staved off cancer for 10 months-double the time Faslodex plus placebo logged-and helped patients live a median of six months longer. The phase 2 data, presented Tuesday at the annual meeting of the American Society for Clinical Oncology, show that blocking AKT-a critical pathway that regulates estrogen receptor (ER) function-along with anti-estrogen therapy is resulting in improved outcomes in these patients,José Baselga, AstraZenecas oncology R&D chief, told FierceBiotech.

Spotlight

As biological molecules, DNA and RNA are fragile compounds that can undergo fast degradation if not handled with precaution and stored under optimal conditions. Poor nucleic acid sample quality may have a direct impact on the results of downstream experiments including next generation sequencing (NGS).

Spotlight

As biological molecules, DNA and RNA are fragile compounds that can undergo fast degradation if not handled with precaution and stored under optimal conditions. Poor nucleic acid sample quality may have a direct impact on the results of downstream experiments including next generation sequencing (NGS).

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Roche | January 25, 2021

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