Berkery, Noyes & Co. | October 08, 2021
Entopsis, Inc., the developer of an unbiased approach to diagnostics using bio-molecular signatures with a focus on oncology, announced that it has engaged Berkery Noyes & Co. as its financial advisor to assist the company in pursuing strategic alternatives for their OpsisDxTM platform.
OpsisDxTM is a urine-based technology platform that shifts the focus away from conventional RNA and DNA approaches, offering a highly sensitive and specific diagnostic test for the detection of early-stage cancers. Its IP-protected platform detects urine chemical signatures via a proprietary array, achieving clinically significant results through its proprietary machine learning algorithms. Validation studies on OpsisDxTM have initially focused on detecting early-stage cancers, and the platform has now expanded to detecting multiple other diseases in a highly scalable fashion.
Now is the time to launch OpsisDxTM. There's greater acceptance of multi-disease testing platforms from a scientific, regulatory and business perspective; the industry as a whole has crossed the tipping point, We are seeking an established partner who shares our vision of empowering people with actionable, low costs and accurate healthcare information with an eye towards the long-term interests of Entopsis.
- Obdulio Piloto, CEO of Entopsis Inc.
Entopsis utilizes a proprietary material science screening platform to develop cost-effective and impactful products.
Adcentrx Therapeutics | February 15, 2022
Adcentrx Therapeutics a biotechnology company focused on accelerating breakthroughs in antibody drug conjugate ("ADC") therapeutic development, and AvantGen, a leader in the use of yeast display technology for human antibody discovery and optimization, announced today a three-year, multi-target partnership for the discovery of antibodies to be developed into novel ADC therapeutic candidates.
Under the terms of the collaboration, Adcentrx will specify targets against which AvantGen will screen for novel antibodies using its yeast display system. Adcentrx will be responsible for engineering the antibodies into ADC therapeutic candidates and has worldwide development and commercialization rights. AvantGen will be eligible to receive milestone payments for achievement of certain development milestones.
"We are excited to enter this new partnership with AvantGen to accelerate our ADC development efforts. What attracted us to AvantGen initially is how their yeast display technology and human antibody libraries mimic human diversity to yield high affinity and very specific antibodies. Through our ongoing collaboration, AvantGen has demonstrated its capabilities in rapidly discovering a diverse antibody repertoire with high developability against defined targets. A key objective at Adcentrx, through this collaboration and opportunistic licensing activities, is to identify the best antibodies which we can leverage to assemble a pipeline of next generation ADC therapeutics."
Hui Li, Ph.D., President and CEO of Adcentrx
"We are proud to partner with Adcentrx to help accelerate its ADC pipeline build with our robust human antibody discovery platform," said Xiaomin Fan, Ph.D., President and CEO of AvantGen. "The speed that Adcentrx is able to take lead antibody candidates to development stage with its ADC technology is truly remarkable. We believe that this new partnership will enable Adcentrx to develop the most promising next generation ADC therapeutics with our high-quality antibodies."
About Adcentrx Therapeutics
Adcentrx is a biotechnology company focused on accelerating breakthroughs in protein conjugate therapeutic development for cancer and other life-threatening diseases. By combining the targeting precision of biologics and the disease fighting power of small molecule payloads, Adcentrx strives to develop next generation targeted therapies for improving patient treatment options.
AvantGen, Inc is a leader in the use of yeast display technology for antibody discovery and optimization. Founded by experts in the creation of antibody discovery and optimization platforms, AvantGen excels in the rapid generation of antibodies for therapeutic, diagnostic and research tool applications. The Company's platforms include a robust yeast display system, large natural human antibody database, fully human antibody libraries comprised of over 100 billion antibody clones displayed by yeast cells, NK cell engager technology, flow cytometry-based and other screening technologies, as well as novel methodologies for rabbit monoclonal antibody and VHH nanobody generation. These versatile platforms can be used to discover antibodies directed at specific disease targets, affinity mature existing antibodies to improve their binding properties and humanize antibodies to render non-human antibodies suitable for human therapeutic applications, as well as generate rabbit monoclonal antibodies for applications that need extremely high specificity, such as antibodies capable of distinguishing point mutations and post-translational modifications for IHC, and anti-idiotype antibodies for PK studies. AvantGen's partners include pharmaceutical, biotech, diagnostic and government entities, many of which are repeat customers.
Bio Detection K9 | May 19, 2022
Bio Detection K9 (BDK9) is pleased to announce its upcoming detection service for Leafroll and Red Blotch Virus in grapes. Of the 86 different viruses known to infect vineyards, Leafroll 3 and Red Blotch virus are among the most prevalent. These pathogens can infect all wine, table and rootstock grapes. They occur in grape production areas around the world and are responsible for causing over 70 billion dollars of damage in the United States alone.
To combat these insidious diseases, BDK9 is launching a cost-effective service that can quickly and accurately pinpoint infected vines before the pathogens have a chance to spread. Utilizing proprietary technology, BDK9 develops training aids that have the scent of the target viruses. The result is a harmless substance with a highly specific scent that dogs are systematically trained to detect. This is the same proven methodology BDK9 employs to screen humans for COVID-19 at airports, stadiums and public events worldwide.
The challenge is like finding a needle in a haystack when trying to detect an infected plant among thousands of potentially threatened vines, But thanks to our completely safe training aid, we can teach canines to accurately detect a viral disease in any tissue, roots, vines, or leaves."
Dr. William Schneider, Chief Research Scientist for BDK9.
BDK9's unique technology is effective in many different areas, from humans to agriculture, and the company is proud to be at the forefront of disease detection.
We're thrilled about the release of this new, cutting-edge technology and are pleased to offer this to the wine industry, Our company continues to set the standard in agriculture disease detection with our effective programs, and we take great pride in the fact that we're able to take action and truly address these important issues as they arise. "
Wade Morrell, CEO of BDK9.
About Bio Detection K9
Bio Detection K9 (BDK9) is the world leader in precision agriculture and human host pathogen bio detection. Led by a veteran USDA virologist, BDK9 works with canines and cutting-edge technology to identify disease in both humans and agriculture. Their dogs are trained to isolate individual pathogens with unparalleled accuracy and specificity. All training is performed safely and Bio Detection Canines™ are unharmed during the process. BDK9 is not only at the forefront of precision pathogen detection through this unique combination of technology and training, but their services are efficient, cost effective and non-invasive.