Salix grabs ex-Asia rights to Mitsubishi Tanabe autoimmune drug

NICK PAUL TAYLOR | April 25, 2019

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Salix Pharmaceuticals has bagged the ex-Asia rights to Mitsubishi Tanabe’s late-phase autoimmune drug, amiselimod. The Bausch Health subsidiary plans to trial the S1P receptor functional antagonist in ulcerative colitis. Amiselimod is designed to inhibit the receptor function of the lymphocyte S1P receptor and thereby keep lymphocytes sequestered in lymph nodes. Through this mechanism, Salix thinks amiselimod will stop the lymphocytes from contributing to immune reactions, leading to improved outcomes in people with conditions including ulcerative colitis.

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MEDICAL

Better Purification and Recovery in Bioprocessing

Article | August 2, 2021

In the downstream portion of any bioprocess, one must pick through the dross before one can seize the gold the biotherapeutic that the bioprocess was always meant to generate. Unfortunately, the dross is both voluminous and various. And the biotherapeutic gold, unlike real gold, is corruptible. That is, it can suffer structural damage and activity loss. When discarding the dross and collecting the gold, bioprocessors must be efficient and gentle. They must, to the extent possible, eliminate contaminants and organic debris while ensuring that biotherapeutics avoid aggregation-inducing stresses and retain their integrity during purification and recovery. Anything less compromises purity and reduces yield. To purify and recover biotherapeutics efficiently and gently, bioprocessors must avail themselves of the most appropriate tools and techniques. Here, we talk with several experts about which tools and techniques can help bioprocessors overcome persistent challenges. Some of these experts also touch on new approaches that can help bioprocessors address emerging challenges.

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DIAGNOSTICS

Making Predictions by Digitizing Bioprocessing

Article | April 20, 2021

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Amplycell

Ever had a promising cell line which just did not perform ? A cell line which does not produce enough, or long enough? Amplycell is a biotech service company of which mission is to optimize recombinant protein and monoclonal antibody productions for Diagnostic and Pharmaceutical firms.

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